The effectiveness of Irifrin 2.5 % and Irifrin-BK 2.5 % drugs in the treatment of computer vision syndrome

Purpose: to assess the results of treatment of patients with computer visual syndrome (CVS) accompanied by low and mild myopia. Material and methods. 52 CVS patients aged 17 to 34 years (mean age 22.3 ± 2.72 years) were divided into 2 groups. For 4 weeks, patients in group 1 received Irifrin 2.5 % a...

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Main Authors: E. L. Efimova, V. V. Brzhesky, I. E. Panova, A. S. Aleksandrova, M. A. Zercalova, Ya. M. Poroger
Format: Article
Language:Russian
Published: Real Time Ltd 2018-10-01
Series:Российский офтальмологический журнал
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Online Access:https://roj.igb.ru/jour/article/view/80
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author E. L. Efimova
V. V. Brzhesky
I. E. Panova
A. S. Aleksandrova
M. A. Zercalova
Ya. M. Poroger
author_facet E. L. Efimova
V. V. Brzhesky
I. E. Panova
A. S. Aleksandrova
M. A. Zercalova
Ya. M. Poroger
author_sort E. L. Efimova
collection DOAJ
description Purpose: to assess the results of treatment of patients with computer visual syndrome (CVS) accompanied by low and mild myopia. Material and methods. 52 CVS patients aged 17 to 34 years (mean age 22.3 ± 2.72 years) were divided into 2 groups. For 4 weeks, patients in group 1 received Irifrin 2.5 % and patients in group 2 received preservative-free Irifrin-BK 2.5 % daily before going to bed. Before and after the course of treatment, all patients were examined to see how Irifrin 2.5 % and Irifrin-BK 2.5 % affect the main accommodation parameters: tear production, tear film stability and ocular surface epithelium. Results. The effectiveness of Irifrin 2.5 % medication was established for both pathogenetic links of CVS: disorders of accommodation and accommodative asthenopia related with it and the secondary “dry eye” syndrome. All patients demonstrated a decrease in the frequency and severity of asthenopia manifestations, increased uncorrected visual acuity, the absolute accommodation volume, as well as positive and negative parts of volume relative accommodation volume, which can be associated with the effect produced by phenylephrine hydrochloride. Besides, a reduction of the subjective discomfort is noted. Corneal epithelial staining with sodium fluorescein and conjunctiva staining with rose Bengal solution becomes less pronounced. Precorneal tear film demonstrates increased stability. These effects are apparently due to the presence of hydroxypropylmethyl cellulose in both drugs and the absence of preservative in Irifrin-BK 2.5 % // Russian Ophthalmological Journal, 2017; 1: 74-9. doi: 10.21516/2072-0076-2017-10-1-74-79.
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spelling doaj-art-7346b85b657c4e4d8cdbbf1779eb29422025-08-20T03:39:45ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602018-10-01101747910.21516/2072-0076-2017-10-1-74-7980The effectiveness of Irifrin 2.5 % and Irifrin-BK 2.5 % drugs in the treatment of computer vision syndromeE. L. Efimova0V. V. Brzhesky1I. E. Panova2A. S. Aleksandrova3M. A. Zercalova4Ya. M. Poroger5St. Petersburg State Pediatric Medical University, St. Petersburg, RussiaSt. Petersburg State Pediatric Medical University, St. Petersburg, RussiaThe St. Petersburg Branch of the S. Fyodorov Eye Microsurgery Federal State Institution, St. Petersburg, RussiaSt. Petersburg State Pediatric Medical University, St. Petersburg, RussiaSt. Petersburg State Pediatric Medical University, St. Petersburg, RussiaMedical center “All Medicine Clinic”, Chelyabinsk, RussiaPurpose: to assess the results of treatment of patients with computer visual syndrome (CVS) accompanied by low and mild myopia. Material and methods. 52 CVS patients aged 17 to 34 years (mean age 22.3 ± 2.72 years) were divided into 2 groups. For 4 weeks, patients in group 1 received Irifrin 2.5 % and patients in group 2 received preservative-free Irifrin-BK 2.5 % daily before going to bed. Before and after the course of treatment, all patients were examined to see how Irifrin 2.5 % and Irifrin-BK 2.5 % affect the main accommodation parameters: tear production, tear film stability and ocular surface epithelium. Results. The effectiveness of Irifrin 2.5 % medication was established for both pathogenetic links of CVS: disorders of accommodation and accommodative asthenopia related with it and the secondary “dry eye” syndrome. All patients demonstrated a decrease in the frequency and severity of asthenopia manifestations, increased uncorrected visual acuity, the absolute accommodation volume, as well as positive and negative parts of volume relative accommodation volume, which can be associated with the effect produced by phenylephrine hydrochloride. Besides, a reduction of the subjective discomfort is noted. Corneal epithelial staining with sodium fluorescein and conjunctiva staining with rose Bengal solution becomes less pronounced. Precorneal tear film demonstrates increased stability. These effects are apparently due to the presence of hydroxypropylmethyl cellulose in both drugs and the absence of preservative in Irifrin-BK 2.5 % // Russian Ophthalmological Journal, 2017; 1: 74-9. doi: 10.21516/2072-0076-2017-10-1-74-79.https://roj.igb.ru/jour/article/view/80компьютерный зрительный синдромсиндром сухого глазааккомодацияирифринирифрин-бкcomputer visual syndromedry eye syndromeaccommodationirifrinirifrin-bk
spellingShingle E. L. Efimova
V. V. Brzhesky
I. E. Panova
A. S. Aleksandrova
M. A. Zercalova
Ya. M. Poroger
The effectiveness of Irifrin 2.5 % and Irifrin-BK 2.5 % drugs in the treatment of computer vision syndrome
Российский офтальмологический журнал
компьютерный зрительный синдром
синдром сухого глаза
аккомодация
ирифрин
ирифрин-бк
computer visual syndrome
dry eye syndrome
accommodation
irifrin
irifrin-bk
title The effectiveness of Irifrin 2.5 % and Irifrin-BK 2.5 % drugs in the treatment of computer vision syndrome
title_full The effectiveness of Irifrin 2.5 % and Irifrin-BK 2.5 % drugs in the treatment of computer vision syndrome
title_fullStr The effectiveness of Irifrin 2.5 % and Irifrin-BK 2.5 % drugs in the treatment of computer vision syndrome
title_full_unstemmed The effectiveness of Irifrin 2.5 % and Irifrin-BK 2.5 % drugs in the treatment of computer vision syndrome
title_short The effectiveness of Irifrin 2.5 % and Irifrin-BK 2.5 % drugs in the treatment of computer vision syndrome
title_sort effectiveness of irifrin 2 5 and irifrin bk 2 5 drugs in the treatment of computer vision syndrome
topic компьютерный зрительный синдром
синдром сухого глаза
аккомодация
ирифрин
ирифрин-бк
computer visual syndrome
dry eye syndrome
accommodation
irifrin
irifrin-bk
url https://roj.igb.ru/jour/article/view/80
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