Targeting macrophages and ion homeostasis in T2D: new genes and therapeutic pathways identified

Targeting macrophages and ion homeostasis in T2D: new genes and therapeutic pathways identified

IntroductionType 2 diabetes (T2D) is characterized by insulin resistance and chronic inflammation, with macrophages playing a crucial role in pancreatic islet dysfunction. This study explored the intersection of macrophage-specific gene expression and abnormal blood monovalent inorganic cation conce...

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Bibliographic Details
Main Authors:	Lisha Mou, Tony Bowei Wang, Ying Lu, Zijing Wu, Yuxian Chen, Ziqi Luo, Xinyu Wang, Zuhui Pu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Series:	Frontiers in Immunology
Subjects:	type 2 diabetes (T2D) macrophages ion homeostasis immune infiltration ScRNA-seq machine learning
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1514243/full
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