Recovery From Severe Heart Failure in a Patient With Primary Hyperoxaluria Type 1 After Treatment With Lumasiran, Pyridoxine, and Kidney Transplant

Recovery From Severe Heart Failure in a Patient With Primary Hyperoxaluria Type 1 After Treatment With Lumasiran, Pyridoxine, and Kidney Transplant

Combined liver and kidney transplant has long been the only therapeutic option for patients with primary hyperoxaluria type 1 (PH1) and advanced chronic kidney disease. The development of lumasiran, a liver-directed RNA interference therapy, has led to effective reduction of hepatic oxalate producti...

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Main Authors: Mira Choi, Andreas Kahl, Gerlineke Hawkins-van der Cingel, Maria de las Mercedes Noriega, Karin Klingel, Patrick Doeblin, Felix Schoenrath, Kai-Uwe Eckardt, Robert Öllinger, Felix Knauf, Fabian Halleck
Format: Article
Language:English
Published: American College of Physicians 2024-06-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2023.1428
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