MESS to live with schizophrenic parental history: A systematic review of developmental checkpoints.

Parental history of schizophrenia, a complex and multifaceted psychological disorder, is recognized as a well-established risk factor in the development of the disorder among offspring. However, the developmental patterns of such children and adolescents before the onset of the problem have not yet...

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Main Authors: Maryam Khan, Rabia Batool, Uzma Mushtaq, Shakir Iqbal, Sana Shaheen, Aimen Zafar Butt, Anees Ahmed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0313531
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author Maryam Khan
Rabia Batool
Uzma Mushtaq
Shakir Iqbal
Sana Shaheen
Aimen Zafar Butt
Anees Ahmed
author_facet Maryam Khan
Rabia Batool
Uzma Mushtaq
Shakir Iqbal
Sana Shaheen
Aimen Zafar Butt
Anees Ahmed
author_sort Maryam Khan
collection DOAJ
description Parental history of schizophrenia, a complex and multifaceted psychological disorder, is recognized as a well-established risk factor in the development of the disorder among offspring. However, the developmental patterns of such children and adolescents before the onset of the problem have not yet been systematically documented. We present a comprehensive account of developmental checkpoints essential for preventing it from occurring. This review embarks on a detailed explanation of the domains requiring serious attention during the development of an individual with such a familial history. We examined a diversified set of studies comparing the developmental patterns of children with or without (a comparative) a parental history of schizophrenia and highlighted the areas of concern for the later development of the problem among the first group. We included the peer-reviewed articles, published in English based on children and adolescents, found in Web of Science, PubMed, and PsychInfo databases and separate citation searches. We summarized our findings under MESS typology covering motor development, emotional and behavioral issues, speech and hearing impairments, and socio-cognitive aspects as essential features of a child's development serving as a guide to prevent the onset of psychological complications.
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spelling doaj-art-733b268242f54519a48c5351b2f587282025-02-05T05:31:24ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01201e031353110.1371/journal.pone.0313531MESS to live with schizophrenic parental history: A systematic review of developmental checkpoints.Maryam KhanRabia BatoolUzma MushtaqShakir IqbalSana ShaheenAimen Zafar ButtAnees AhmedParental history of schizophrenia, a complex and multifaceted psychological disorder, is recognized as a well-established risk factor in the development of the disorder among offspring. However, the developmental patterns of such children and adolescents before the onset of the problem have not yet been systematically documented. We present a comprehensive account of developmental checkpoints essential for preventing it from occurring. This review embarks on a detailed explanation of the domains requiring serious attention during the development of an individual with such a familial history. We examined a diversified set of studies comparing the developmental patterns of children with or without (a comparative) a parental history of schizophrenia and highlighted the areas of concern for the later development of the problem among the first group. We included the peer-reviewed articles, published in English based on children and adolescents, found in Web of Science, PubMed, and PsychInfo databases and separate citation searches. We summarized our findings under MESS typology covering motor development, emotional and behavioral issues, speech and hearing impairments, and socio-cognitive aspects as essential features of a child's development serving as a guide to prevent the onset of psychological complications.https://doi.org/10.1371/journal.pone.0313531
spellingShingle Maryam Khan
Rabia Batool
Uzma Mushtaq
Shakir Iqbal
Sana Shaheen
Aimen Zafar Butt
Anees Ahmed
MESS to live with schizophrenic parental history: A systematic review of developmental checkpoints.
PLoS ONE
title MESS to live with schizophrenic parental history: A systematic review of developmental checkpoints.
title_full MESS to live with schizophrenic parental history: A systematic review of developmental checkpoints.
title_fullStr MESS to live with schizophrenic parental history: A systematic review of developmental checkpoints.
title_full_unstemmed MESS to live with schizophrenic parental history: A systematic review of developmental checkpoints.
title_short MESS to live with schizophrenic parental history: A systematic review of developmental checkpoints.
title_sort mess to live with schizophrenic parental history a systematic review of developmental checkpoints
url https://doi.org/10.1371/journal.pone.0313531
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