Exploration of potential biomarkers and immune cell infiltration characteristics for peripheral atherosclerosis in sjögren’s syndrome based on comprehensive bioinformatics analysis and machine learning

Exploration of potential biomarkers and immune cell infiltration characteristics for peripheral atherosclerosis in sjögren’s syndrome based on comprehensive bioinformatics analysis and machine learning

BackgroundSjögren’s syndrome (SS) is an autoimmune disorder impacting exocrine glands, while peripheral atherosclerosis (PA) demonstrates a close link to inflammation. Despite a notable rise in atherosclerosis risk among SS patients in prior investigations, the precise mechanisms remain elusive.Meth...

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Bibliographic Details
Main Authors: Chunjiang Liu, Yuan Wang, Lina Zhou, Feifei Cai, Xiaoqi Tang, Liying Wang, Xiang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Genetics
Subjects:
peripheral atherosclerosis
Sjögren’s syndrome
biomarkers
immune infiltration
bioinformatics analysis
machine learning
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1546315/full
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