A Rare Case of Steroid Cell Tumor, Not Otherwise Specified (NOS), of the Ovary in a Young Woman

Steroid cell tumour is a rare sex cord-stromal tumor of the ovary. It may produce steroids and is associated with testosterone secretion which causes symptoms like hair loss, hirsutism, and oligomenorrhea/amenorrhea due to hormonal activity and virilizing properties of tumor. In this article, we rep...

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Main Authors: Eek Chaw Tan, Chit Chong Khong, Kazila Bhutia
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2019/4375839
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author Eek Chaw Tan
Chit Chong Khong
Kazila Bhutia
author_facet Eek Chaw Tan
Chit Chong Khong
Kazila Bhutia
author_sort Eek Chaw Tan
collection DOAJ
description Steroid cell tumour is a rare sex cord-stromal tumor of the ovary. It may produce steroids and is associated with testosterone secretion which causes symptoms like hair loss, hirsutism, and oligomenorrhea/amenorrhea due to hormonal activity and virilizing properties of tumor. In this article, we reported a 27-year-old woman who presented with hirsutism, hoarseness of voice, scalp hair fall, and amenorrhea for 8 years. Clinical and diagnostic evaluation revealed a left adnexal mass and elevated serum levels of testosterone and she was diagnosed as having a Sertoli Leydig cell tumour of ovary. She underwent left salpingooophorectomy and both histopathological examination and immunohistochemistry confirmed the diagnosis. Her serum testosterone levels normalized 3 days after the surgery and her menses resumed spontaneously a few months after the operation. In addition, we reviewed the literature on the epidemiology, clinical presentations, imaging and histological findings, and the treatment options on this disease.
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spelling doaj-art-73362ea561e44fcfba8670501b1ad09a2025-08-20T02:06:19ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922019-01-01201910.1155/2019/43758394375839A Rare Case of Steroid Cell Tumor, Not Otherwise Specified (NOS), of the Ovary in a Young WomanEek Chaw Tan0Chit Chong Khong1Kazila Bhutia2Division of Obstetrics & Gynaecology, KK Women’s and Children’s Hospital, SingaporeDivision of Obstetrics & Gynaecology, KK Women’s and Children’s Hospital, SingaporeDivision of Obstetrics & Gynaecology, KK Women’s and Children’s Hospital, SingaporeSteroid cell tumour is a rare sex cord-stromal tumor of the ovary. It may produce steroids and is associated with testosterone secretion which causes symptoms like hair loss, hirsutism, and oligomenorrhea/amenorrhea due to hormonal activity and virilizing properties of tumor. In this article, we reported a 27-year-old woman who presented with hirsutism, hoarseness of voice, scalp hair fall, and amenorrhea for 8 years. Clinical and diagnostic evaluation revealed a left adnexal mass and elevated serum levels of testosterone and she was diagnosed as having a Sertoli Leydig cell tumour of ovary. She underwent left salpingooophorectomy and both histopathological examination and immunohistochemistry confirmed the diagnosis. Her serum testosterone levels normalized 3 days after the surgery and her menses resumed spontaneously a few months after the operation. In addition, we reviewed the literature on the epidemiology, clinical presentations, imaging and histological findings, and the treatment options on this disease.http://dx.doi.org/10.1155/2019/4375839
spellingShingle Eek Chaw Tan
Chit Chong Khong
Kazila Bhutia
A Rare Case of Steroid Cell Tumor, Not Otherwise Specified (NOS), of the Ovary in a Young Woman
Case Reports in Obstetrics and Gynecology
title A Rare Case of Steroid Cell Tumor, Not Otherwise Specified (NOS), of the Ovary in a Young Woman
title_full A Rare Case of Steroid Cell Tumor, Not Otherwise Specified (NOS), of the Ovary in a Young Woman
title_fullStr A Rare Case of Steroid Cell Tumor, Not Otherwise Specified (NOS), of the Ovary in a Young Woman
title_full_unstemmed A Rare Case of Steroid Cell Tumor, Not Otherwise Specified (NOS), of the Ovary in a Young Woman
title_short A Rare Case of Steroid Cell Tumor, Not Otherwise Specified (NOS), of the Ovary in a Young Woman
title_sort rare case of steroid cell tumor not otherwise specified nos of the ovary in a young woman
url http://dx.doi.org/10.1155/2019/4375839
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