AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-08-01
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| Series: | Signal Transduction and Targeted Therapy |
| Online Access: | https://doi.org/10.1038/s41392-025-02336-2 |
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| _version_ | 1849235554534686720 |
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| author | Navin Gupta Ke Zhang Venkata Sabbisetti Jian Shu Ryuji Morizane |
| author_facet | Navin Gupta Ke Zhang Venkata Sabbisetti Jian Shu Ryuji Morizane |
| author_sort | Navin Gupta |
| collection | DOAJ |
| format | Article |
| id | doaj-art-733448df052c4874a6a017d5eafe8d41 |
| institution | Kabale University |
| issn | 2059-3635 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Signal Transduction and Targeted Therapy |
| spelling | doaj-art-733448df052c4874a6a017d5eafe8d412025-08-20T04:02:45ZengNature Publishing GroupSignal Transduction and Targeted Therapy2059-36352025-08-011011410.1038/s41392-025-02336-2AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoidsNavin Gupta0Ke Zhang1Venkata Sabbisetti2Jian Shu3Ryuji Morizane4Nephrology Division, Department of Medicine, Mass General Brigham, Harvard Medical SchoolCutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical SchoolNephrology Division, Department of Medicine, Mass General Brigham, Harvard Medical SchoolCutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical SchoolNephrology Division, Department of Medicine, Mass General Brigham, Harvard Medical Schoolhttps://doi.org/10.1038/s41392-025-02336-2 |
| spellingShingle | Navin Gupta Ke Zhang Venkata Sabbisetti Jian Shu Ryuji Morizane AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids Signal Transduction and Targeted Therapy |
| title | AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids |
| title_full | AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids |
| title_fullStr | AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids |
| title_full_unstemmed | AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids |
| title_short | AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids |
| title_sort | aav for gene therapy drives a nephrotoxic response via nfκb in kidney organoids |
| url | https://doi.org/10.1038/s41392-025-02336-2 |
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