Clinical usefulness of anti-α3Gal immunoglobulin E assays for cetuximab-mediated anaphylaxis in head and neck cancer

Clinical usefulness of anti-α3Gal immunoglobulin E assays for cetuximab-mediated anaphylaxis in head and neck cancer

Background: Fatal anaphylactic reactions to cetuximab remain a clinical issue, although they are associated with preexisting immunoglobulin E (IgE) directed against the galactose-α1,3-galactose epitope (α3Gal). We aimed to compare the clinical usefulness of the two assays and determine the prevalenc...

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Bibliographic Details
Main Authors: Y. Pointreau, C. Freneaux, T. Bejan-Angoulvant, D. Ternant, G. Calais, H. Watier
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Immuno-Oncology and Technology
Subjects:
cetuximab
infusion reaction
hypersensitivity assays
head and neck cancer
anti-α3Gal IgE
Online Access:http://www.sciencedirect.com/science/article/pii/S2590018825000012
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