Type 2 Myocardial Infarction in a Sub‐Saharan Africa Population: Challenging the Current Concepts—Data From REACTIV
Background From a large observational acute coronary syndrome registry in Côte d'Ivoire, we aimed to assess incidence, clinical presentation, management, and in‐hospital outcomes for type 2 myocardial infarction (T2MI) compared with type 1 MI. Methods and Results We conducted a cross‐sectional...
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Wiley
2024-07-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
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| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.123.032149 |
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| author | Hermann Yao Camille Touré Arnaud Ekou Elvis Sepih Yves Cottin Marianne Zeller Alain Putot Roland N'Guetta |
| author_facet | Hermann Yao Camille Touré Arnaud Ekou Elvis Sepih Yves Cottin Marianne Zeller Alain Putot Roland N'Guetta |
| author_sort | Hermann Yao |
| collection | DOAJ |
| description | Background From a large observational acute coronary syndrome registry in Côte d'Ivoire, we aimed to assess incidence, clinical presentation, management, and in‐hospital outcomes for type 2 myocardial infarction (T2MI) compared with type 1 MI. Methods and Results We conducted a cross‐sectional monocentric study using data from REACTIV (Registre des Infarctus de Côte d'Ivoire) at the Abidjan Heart Institute. All patients hospitalized with MI between 2018 and 2022 who underwent coronary angiography were included. For each patient, sociodemographic data, cardiovascular risk factors and history, and clinical and paraclinical presentation were collected at admission. In‐hospital outcomes, including major adverse cardiovascular events and mortality, were reported. Among 541 consecutive patients hospitalized with MI, 441 met the definition of type 1 MI or T2MI. T2MI accounted for 14.1% of cases. Patients with T2MI showed a trend toward slightly younger age (54 versus 58 years, P=0.09). Patients with T2MI seemed to have less severe coronary artery disease, with less frequent multivessel disease (P<0.001). Main triggering factors for T2MI were coronary embolism (24.2%), severe hypertension with or without left ventricular hypertrophy (22.6%), and tachyarrhythmia (16.1%). In‐hospital event rates were low in both MI types. Although the difference was nonsignificant, death rates for patients with type 1 MI tended to be higher than for patients with T2MI, as well as occurrence of major adverse cardiovascular events. Conclusions Our study revealed disparities in clinical characteristics, angiographic features, cause, and in‐hospital outcomes in T2MI in our population compared with Western populations. These results suggest the heterogeneity of T2MI and the potential causative and demographic variability depending on geographical area. |
| format | Article |
| id | doaj-art-7316fc178db1477ab32aee0f441e5591 |
| institution | DOAJ |
| issn | 2047-9980 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj-art-7316fc178db1477ab32aee0f441e55912025-08-20T03:10:10ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802024-07-01131410.1161/JAHA.123.032149Type 2 Myocardial Infarction in a Sub‐Saharan Africa Population: Challenging the Current Concepts—Data From REACTIVHermann Yao0Camille Touré1Arnaud Ekou2Elvis Sepih3Yves Cottin4Marianne Zeller5Alain Putot6Roland N'Guetta7PEC2, EA 7460, UFR Health Sciences University of Bourgogne Franche Comté Dijon FranceAbidjan Heart Institute Abidjan Côte d’IvoireAbidjan Heart Institute Abidjan Côte d’IvoireAbidjan Heart Institute Abidjan Côte d’IvoireCardiology Department University Hospital Center Dijon Bourgogne Dijon FrancePEC2, EA 7460, UFR Health Sciences University of Bourgogne Franche Comté Dijon FrancePEC2, EA 7460, UFR Health Sciences University of Bourgogne Franche Comté Dijon FranceAbidjan Heart Institute Abidjan Côte d’IvoireBackground From a large observational acute coronary syndrome registry in Côte d'Ivoire, we aimed to assess incidence, clinical presentation, management, and in‐hospital outcomes for type 2 myocardial infarction (T2MI) compared with type 1 MI. Methods and Results We conducted a cross‐sectional monocentric study using data from REACTIV (Registre des Infarctus de Côte d'Ivoire) at the Abidjan Heart Institute. All patients hospitalized with MI between 2018 and 2022 who underwent coronary angiography were included. For each patient, sociodemographic data, cardiovascular risk factors and history, and clinical and paraclinical presentation were collected at admission. In‐hospital outcomes, including major adverse cardiovascular events and mortality, were reported. Among 541 consecutive patients hospitalized with MI, 441 met the definition of type 1 MI or T2MI. T2MI accounted for 14.1% of cases. Patients with T2MI showed a trend toward slightly younger age (54 versus 58 years, P=0.09). Patients with T2MI seemed to have less severe coronary artery disease, with less frequent multivessel disease (P<0.001). Main triggering factors for T2MI were coronary embolism (24.2%), severe hypertension with or without left ventricular hypertrophy (22.6%), and tachyarrhythmia (16.1%). In‐hospital event rates were low in both MI types. Although the difference was nonsignificant, death rates for patients with type 1 MI tended to be higher than for patients with T2MI, as well as occurrence of major adverse cardiovascular events. Conclusions Our study revealed disparities in clinical characteristics, angiographic features, cause, and in‐hospital outcomes in T2MI in our population compared with Western populations. These results suggest the heterogeneity of T2MI and the potential causative and demographic variability depending on geographical area.https://www.ahajournals.org/doi/10.1161/JAHA.123.032149coronary artery diseasesub‐Saharan Africatype 1 myocardial infarctiontype 2 myocardial infarction |
| spellingShingle | Hermann Yao Camille Touré Arnaud Ekou Elvis Sepih Yves Cottin Marianne Zeller Alain Putot Roland N'Guetta Type 2 Myocardial Infarction in a Sub‐Saharan Africa Population: Challenging the Current Concepts—Data From REACTIV Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease coronary artery disease sub‐Saharan Africa type 1 myocardial infarction type 2 myocardial infarction |
| title | Type 2 Myocardial Infarction in a Sub‐Saharan Africa Population: Challenging the Current Concepts—Data From REACTIV |
| title_full | Type 2 Myocardial Infarction in a Sub‐Saharan Africa Population: Challenging the Current Concepts—Data From REACTIV |
| title_fullStr | Type 2 Myocardial Infarction in a Sub‐Saharan Africa Population: Challenging the Current Concepts—Data From REACTIV |
| title_full_unstemmed | Type 2 Myocardial Infarction in a Sub‐Saharan Africa Population: Challenging the Current Concepts—Data From REACTIV |
| title_short | Type 2 Myocardial Infarction in a Sub‐Saharan Africa Population: Challenging the Current Concepts—Data From REACTIV |
| title_sort | type 2 myocardial infarction in a sub saharan africa population challenging the current concepts data from reactiv |
| topic | coronary artery disease sub‐Saharan Africa type 1 myocardial infarction type 2 myocardial infarction |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.123.032149 |
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