Nationwide implementation of the international multidisciplinary best-practice for locally advanced pancreatic cancer (PREOPANC-4): study protocol

Nationwide implementation of the international multidisciplinary best-practice for locally advanced pancreatic cancer (PREOPANC-4): study protocol

Abstract Background The introduction of (m)FOLFIRINOX and gemcitabine-nab-paclitaxel has changed the perspective for patients with locally advanced pancreatic cancer (LAPC). Consequently, in experienced centres 23% of patients with LAPC undergo a resection with 5-year overall survival (OS) rates of...

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Main Authors: T. F. Stoop, L. W. F. Seelen, F. R. van ’t Land, A. C. van der Hout, J. C. M. Scheepens, M. Ali, A. M. Stiggelbout, B. M. van der Kolk, B. A. Bonsing, D. J. Lips, D. J. A. de Groot, E. van Veldhuisen, E. D. Kerver, E. R. Manusama, F. Daams, G. Kazemier, G. A. Cirkel, G. van Tienhoven, G. A. Patijn, H. N. Lelieveld-Rier, I. H. de Hingh, I. E. G. van Hellemond, J. H. Wijsman, J. I. Erdmann, J. S. D. Mieog, J. de Vos-Geelen, J. W. B. de Groot, K. R. D. Lutchman, L. J. Mekenkamp, L. W. Kranenburg, L. P. M. Beuk, M. W. Nijkamp, M. den Dulk, M. B. Polée, M. Y. V. Homs, M. L. Wumkes, M. W. J. Stommel, O. R. Busch, R. F. de Wilde, R. T. Theijse, S. A. C. Luelmo, S. Festen, T. L. Bollen, U. P. Neumann, V. E. de Meijer, W. A. Draaisma, B. Groot Koerkamp, I. Q. Molenaar, C. L. Wolfgang, M. Del Chiaro, M. G. H. Katz, T. Hackert, J. A. C. Rietjens, J. W. Wilmink, H. C. van Santvoort, C. H. J. van Eijck, M. G. Besselink, for the Dutch Pancreatic Cancer Group
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
Subjects:
Locally advanced pancreatic cancer
Induction therapy
Surgery
Implementation program
The Netherlands
Online Access:https://doi.org/10.1186/s12885-025-13554-w
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