Single trial Bayesian inference by population vector readout in the barn owl's sound localization system.

Bayesian models have proven effective in characterizing perception, behavior, and neural encoding across diverse species and systems. The neural implementation of Bayesian inference in the barn owl's sound localization system and behavior has been previously explained by a non-uniform populatio...

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Main Authors: Brian J Fischer, Keanu Shadron, Roland Ferger, José L Peña
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0303843&type=printable
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author Brian J Fischer
Keanu Shadron
Roland Ferger
José L Peña
author_facet Brian J Fischer
Keanu Shadron
Roland Ferger
José L Peña
author_sort Brian J Fischer
collection DOAJ
description Bayesian models have proven effective in characterizing perception, behavior, and neural encoding across diverse species and systems. The neural implementation of Bayesian inference in the barn owl's sound localization system and behavior has been previously explained by a non-uniform population code model. This model specifies the neural population activity pattern required for a population vector readout to match the optimal Bayesian estimate. While prior analyses focused on trial-averaged comparisons of model predictions with behavior and single-neuron responses, it remains unknown whether this model can accurately approximate Bayesian inference on single trials under varying sensory reliability, a fundamental condition for natural perception and behavior. In this study, we utilized mathematical analysis and simulations to demonstrate that decoding a non-uniform population code via a population vector readout approximates the Bayesian estimate on single trials for varying sensory reliabilities. Our findings provide additional support for the non-uniform population code model as a viable explanation for the barn owl's sound localization pathway and behavior.
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issn 1932-6203
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spelling doaj-art-730dbfd3e5c44d52b06d09d12e33cdb12025-08-20T03:25:59ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-01195e030384310.1371/journal.pone.0303843Single trial Bayesian inference by population vector readout in the barn owl's sound localization system.Brian J FischerKeanu ShadronRoland FergerJosé L PeñaBayesian models have proven effective in characterizing perception, behavior, and neural encoding across diverse species and systems. The neural implementation of Bayesian inference in the barn owl's sound localization system and behavior has been previously explained by a non-uniform population code model. This model specifies the neural population activity pattern required for a population vector readout to match the optimal Bayesian estimate. While prior analyses focused on trial-averaged comparisons of model predictions with behavior and single-neuron responses, it remains unknown whether this model can accurately approximate Bayesian inference on single trials under varying sensory reliability, a fundamental condition for natural perception and behavior. In this study, we utilized mathematical analysis and simulations to demonstrate that decoding a non-uniform population code via a population vector readout approximates the Bayesian estimate on single trials for varying sensory reliabilities. Our findings provide additional support for the non-uniform population code model as a viable explanation for the barn owl's sound localization pathway and behavior.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0303843&type=printable
spellingShingle Brian J Fischer
Keanu Shadron
Roland Ferger
José L Peña
Single trial Bayesian inference by population vector readout in the barn owl's sound localization system.
PLoS ONE
title Single trial Bayesian inference by population vector readout in the barn owl's sound localization system.
title_full Single trial Bayesian inference by population vector readout in the barn owl's sound localization system.
title_fullStr Single trial Bayesian inference by population vector readout in the barn owl's sound localization system.
title_full_unstemmed Single trial Bayesian inference by population vector readout in the barn owl's sound localization system.
title_short Single trial Bayesian inference by population vector readout in the barn owl's sound localization system.
title_sort single trial bayesian inference by population vector readout in the barn owl s sound localization system
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0303843&type=printable
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