Successful treatment of deep corneal abscess with serial intrastromal broad-spectrum antibiotic injection: Case report and literature review
Purpose: To report the case of a male with a deep stromal corneal abscess recalcitrant to topical treatment who presented complete resolution after serial intrastromal broad-spectrum antibiotics injections. Observations: A 66 years old man with a medical history of type 1- neurofibromatosis presente...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-11-01
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| Series: | The Pan-American Journal of Ophthalmology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/pajo.pajo_80_24 |
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| Summary: | Purpose:
To report the case of a male with a deep stromal corneal abscess recalcitrant to topical treatment who presented complete resolution after serial intrastromal broad-spectrum antibiotics injections.
Observations:
A 66 years old man with a medical history of type 1- neurofibromatosis presented with a 1 1-month history of painful vision loss in his right eye. Ophthalmological examination showed a deep limbal corneal abscess with hypopyon, with a best corrected visual acuity of hand movements. The abscess was refractory to complete topical treatment. He underwent 4 interventions with intrastromal injections of 1mg/0.1ml vancomycin and ceftazidime with 15-day intervals each one, associated anterior chamber washout. A complete resolution of infection was established due to clinical and paraclinical improvement evidenced in serial anterior chamber tomographies.
Conclusion:
Treatment of bacterial deep corneal abscess is challenging because of the limited treatment options. There is a lack of evidence about standardized doses of intrastromal injection of antibiotics. |
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| ISSN: | 2666-4909 |