Cold-blooded vertebrates evolved regulatory B cells to participate in inflammatory diseases
Abstract Background Regulatory B cell (Breg), known for its immunosuppressive properties through the provision of IL-10, plays a critical role in the control of inflammatory diseases. Although Breg has been discovered for over two decades in mammals, its existence in non-mammalian vertebrates remain...
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| Main Authors: | Jie Wang, Wen-Jing Dong, Tian-Tian Tian, Chang-Song Wu, Xiang-Yang Zhang, Ya-Zhen Hu, Yi-Ru Pan, Xue-Qing Han, Jun Li, Carolina Tafalla, Yong-An Zhang, Xu-Jie Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
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| Series: | Cell Communication and Signaling |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12964-025-02311-y |
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