Personalized home based neurostimulation via AI optimization augments sustained attention

Abstract Brain-based technologies for human augmentation face challenges in personalization and real-world translation. We present an AI-driven personalized Bayesian optimization algorithm that remotely adjusts neurostimulation parameters based on baseline ability and head anatomy to enhance sustain...

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Main Authors: Roi Cohen Kadosh, Delia Ciobotaru, Malin I. Karstens, Vu Nguyen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-025-01744-6
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author Roi Cohen Kadosh
Delia Ciobotaru
Malin I. Karstens
Vu Nguyen
author_facet Roi Cohen Kadosh
Delia Ciobotaru
Malin I. Karstens
Vu Nguyen
author_sort Roi Cohen Kadosh
collection DOAJ
description Abstract Brain-based technologies for human augmentation face challenges in personalization and real-world translation. We present an AI-driven personalized Bayesian optimization algorithm that remotely adjusts neurostimulation parameters based on baseline ability and head anatomy to enhance sustained attention at home. Validated through in silico modeling and a double-blind, sham-controlled study, our approach aligns with MRI-based models and neurobiological theories, maximizing efficacy and enabling scalable, personalized cognitive enhancement and therapy in real-world settings.
format Article
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institution Kabale University
issn 2398-6352
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publishDate 2025-07-01
publisher Nature Portfolio
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series npj Digital Medicine
spelling doaj-art-7304ce5251cc4cb6a7d97e384b35aa162025-08-20T04:03:11ZengNature Portfolionpj Digital Medicine2398-63522025-07-01811910.1038/s41746-025-01744-6Personalized home based neurostimulation via AI optimization augments sustained attentionRoi Cohen Kadosh0Delia Ciobotaru1Malin I. Karstens2Vu Nguyen3School of Psychology, University of SurreySchool of Psychology, University of SurreyCognite Neurotechnology LtdAmazonAbstract Brain-based technologies for human augmentation face challenges in personalization and real-world translation. We present an AI-driven personalized Bayesian optimization algorithm that remotely adjusts neurostimulation parameters based on baseline ability and head anatomy to enhance sustained attention at home. Validated through in silico modeling and a double-blind, sham-controlled study, our approach aligns with MRI-based models and neurobiological theories, maximizing efficacy and enabling scalable, personalized cognitive enhancement and therapy in real-world settings.https://doi.org/10.1038/s41746-025-01744-6
spellingShingle Roi Cohen Kadosh
Delia Ciobotaru
Malin I. Karstens
Vu Nguyen
Personalized home based neurostimulation via AI optimization augments sustained attention
npj Digital Medicine
title Personalized home based neurostimulation via AI optimization augments sustained attention
title_full Personalized home based neurostimulation via AI optimization augments sustained attention
title_fullStr Personalized home based neurostimulation via AI optimization augments sustained attention
title_full_unstemmed Personalized home based neurostimulation via AI optimization augments sustained attention
title_short Personalized home based neurostimulation via AI optimization augments sustained attention
title_sort personalized home based neurostimulation via ai optimization augments sustained attention
url https://doi.org/10.1038/s41746-025-01744-6
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AT malinikarstens personalizedhomebasedneurostimulationviaaioptimizationaugmentssustainedattention
AT vunguyen personalizedhomebasedneurostimulationviaaioptimizationaugmentssustainedattention