GLYCOSYLATION DISORDER SYNDROME TYPE 1b: DIAGNOSTICS AND TREATMENT

The article highlights the medical case of a rare hereditary disease — glycosylation disorder syndrome type 1b, unique for our country. This syndrome is referred to the heterogeneous group of the congenital diseases characterized by the disorder of glycoprotein synthesis as a result of the defects N...

Full description

Saved in:
Bibliographic Details
Main Authors: Yu.S. Akoev, A.V. Migali, N.V. Zhurkova, O.B. Kondakova, E.A. Roslavtseva, A.R. Pinaeva, V.A. Skvortsova, I.I. Migali
Format: Article
Language:Russian
Published: Union of pediatricians of Russia 2008-09-01
Series:Педиатрическая фармакология
Online Access:https://www.pedpharma.ru/jour/article/view/765
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850046687711592448
author Yu.S. Akoev
A.V. Migali
N.V. Zhurkova
O.B. Kondakova
E.A. Roslavtseva
A.R. Pinaeva
V.A. Skvortsova
I.I. Migali
author_facet Yu.S. Akoev
A.V. Migali
N.V. Zhurkova
O.B. Kondakova
E.A. Roslavtseva
A.R. Pinaeva
V.A. Skvortsova
I.I. Migali
author_sort Yu.S. Akoev
collection DOAJ
description The article highlights the medical case of a rare hereditary disease — glycosylation disorder syndrome type 1b, unique for our country. This syndrome is referred to the heterogeneous group of the congenital diseases characterized by the disorder of glycoprotein synthesis as a result of the defects N or O glycosylation. Manifestations of the disease are protein losing enteropathy and severe developmental delay, hypoglycemia, co agulopathy (thrombosis), liver injury. glycosylation disorder syndrome type 1b differs from other types of this group absence of the neurologic semiology and efficiency of therapy by mannose.Key words: glycoproteins, glycosylation disorders, manifestations, mannose, children.
format Article
id doaj-art-72f8c490202f4fd7be1968f95b008fa3
institution DOAJ
issn 1727-5776
2500-3089
language Russian
publishDate 2008-09-01
publisher Union of pediatricians of Russia
record_format Article
series Педиатрическая фармакология
spelling doaj-art-72f8c490202f4fd7be1968f95b008fa32025-08-20T02:54:23ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892008-09-01553133760GLYCOSYLATION DISORDER SYNDROME TYPE 1b: DIAGNOSTICS AND TREATMENTYu.S. Akoev0A.V. Migali1N.V. Zhurkova2O.B. Kondakova3E.A. Roslavtseva4A.R. Pinaeva5V.A. Skvortsova6I.I. Migali7Scientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowThe article highlights the medical case of a rare hereditary disease — glycosylation disorder syndrome type 1b, unique for our country. This syndrome is referred to the heterogeneous group of the congenital diseases characterized by the disorder of glycoprotein synthesis as a result of the defects N or O glycosylation. Manifestations of the disease are protein losing enteropathy and severe developmental delay, hypoglycemia, co agulopathy (thrombosis), liver injury. glycosylation disorder syndrome type 1b differs from other types of this group absence of the neurologic semiology and efficiency of therapy by mannose.Key words: glycoproteins, glycosylation disorders, manifestations, mannose, children.https://www.pedpharma.ru/jour/article/view/765
spellingShingle Yu.S. Akoev
A.V. Migali
N.V. Zhurkova
O.B. Kondakova
E.A. Roslavtseva
A.R. Pinaeva
V.A. Skvortsova
I.I. Migali
GLYCOSYLATION DISORDER SYNDROME TYPE 1b: DIAGNOSTICS AND TREATMENT
Педиатрическая фармакология
title GLYCOSYLATION DISORDER SYNDROME TYPE 1b: DIAGNOSTICS AND TREATMENT
title_full GLYCOSYLATION DISORDER SYNDROME TYPE 1b: DIAGNOSTICS AND TREATMENT
title_fullStr GLYCOSYLATION DISORDER SYNDROME TYPE 1b: DIAGNOSTICS AND TREATMENT
title_full_unstemmed GLYCOSYLATION DISORDER SYNDROME TYPE 1b: DIAGNOSTICS AND TREATMENT
title_short GLYCOSYLATION DISORDER SYNDROME TYPE 1b: DIAGNOSTICS AND TREATMENT
title_sort glycosylation disorder syndrome type 1b diagnostics and treatment
url https://www.pedpharma.ru/jour/article/view/765
work_keys_str_mv AT yusakoev glycosylationdisordersyndrometype1bdiagnosticsandtreatment
AT avmigali glycosylationdisordersyndrometype1bdiagnosticsandtreatment
AT nvzhurkova glycosylationdisordersyndrometype1bdiagnosticsandtreatment
AT obkondakova glycosylationdisordersyndrometype1bdiagnosticsandtreatment
AT earoslavtseva glycosylationdisordersyndrometype1bdiagnosticsandtreatment
AT arpinaeva glycosylationdisordersyndrometype1bdiagnosticsandtreatment
AT vaskvortsova glycosylationdisordersyndrometype1bdiagnosticsandtreatment
AT iimigali glycosylationdisordersyndrometype1bdiagnosticsandtreatment