Intergenic transcription, cell-cycle and the developmentally regulated epigenetic profile of the human beta-globin locus.
Several lines of evidence have established strong links between transcriptional activity and specific post-translation modifications of histones. Here we show using RNA FISH that in erythroid cells, intergenic transcription in the human beta-globin locus occurs over a region of greater than 250 kb i...
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| Main Authors: | Joanne Miles, Jennifer A Mitchell, Lyubomira Chakalova, Beatriz Goyenechea, Cameron S Osborne, Laura O'Neill, Keiji Tanimoto, James Douglas Engel, Peter Fraser |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-07-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000630&type=printable |
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