Intraocular complement activation is independent of systemic complement activation and is related to macular vascular remodelling in retinal vein occlusion

Intraocular complement activation is independent of systemic complement activation and is related to macular vascular remodelling in retinal vein occlusion

Abstract Background Retinal vein occlusion (RVO) is a major cause of vision loss. The pathogenesis remains poorly defined although inflammation is known to play a critical role. In this study, we investigated the levels of complement proteins in the aqueous humour and plasma of RVO participants and...

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Bibliographic Details
Main Authors: Hengwei Liu, Yufan Zhou, Jinyan Qi, Shengnan Liang, Tingting Guo, Juan Chen, Huanhuan Tan, Jie Wang, Heping Xu, Zhongping Chen
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Ophthalmology
Subjects:
Aqueous humour
Retinal vein occlusion
Complement proteins
Classical pathway
Optical coherence tomographic angiography
Online Access:https://doi.org/10.1186/s12886-024-03781-3
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