Application of Surface Roughness Analysis on Micro–Computed Tomographic Images of Bone Erosion: Examples Using a Rodent Model of Rheumatoid Arthritis

Application of Surface Roughness Analysis on Micro–Computed Tomographic Images of Bone Erosion: Examples Using a Rodent Model of Rheumatoid Arthritis

Quantifying the bone erosion in preclinical models of rheumatoid arthritis is valuable for the evaluation of drug treatments. This study introduces a three-dimensional method for bone surface roughness measurement from micro–computed tomographic data obtained from rats subjected to collagen-induced...

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Bibliographic Details
Main Authors: Matthew D. Silva, Jason Ruan, Elizabeth Siebert, Anneli Savinainen, Bruce Jaffee, Lisa Schopf, Sudeep Chandra
Format: Article
Language:English
Published: SAGE Publishing 2006-10-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2006.00025
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