Bone Integration of Femtosecond Laser-Treated Dental Implants with Nanostructured Surfaces: A Controlled Animal Study

Background: The purpose of this study is to compare bone union and soft-tissue healing in titanium implants with sandblasted, large-grit, acid-etched surfaces (SLA group) and femtosecond laser-treated surfaces (FEMTO group) in a rabbit model. Methods: Implants were inserted into rabbit tibiae, and i...

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Main Authors: Woo-Seok Do, Keun-Ba-Da Son, Young-Tak Son, Yong-Gun Kim, Sung-Min Hwang, Jun-Ho Hwang, Jong-Hoon Lee, Hyun-Deok Kim, Kyu-Bok Lee, Jae-Mok Lee
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Applied Sciences
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Online Access:https://www.mdpi.com/2076-3417/14/23/10913
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author Woo-Seok Do
Keun-Ba-Da Son
Young-Tak Son
Yong-Gun Kim
Sung-Min Hwang
Jun-Ho Hwang
Jong-Hoon Lee
Hyun-Deok Kim
Kyu-Bok Lee
Jae-Mok Lee
author_facet Woo-Seok Do
Keun-Ba-Da Son
Young-Tak Son
Yong-Gun Kim
Sung-Min Hwang
Jun-Ho Hwang
Jong-Hoon Lee
Hyun-Deok Kim
Kyu-Bok Lee
Jae-Mok Lee
author_sort Woo-Seok Do
collection DOAJ
description Background: The purpose of this study is to compare bone union and soft-tissue healing in titanium implants with sandblasted, large-grit, acid-etched surfaces (SLA group) and femtosecond laser-treated surfaces (FEMTO group) in a rabbit model. Methods: Implants were inserted into rabbit tibiae, and implant stability, soft-tissue healing, and microscopic analyses (micro-CT and biopsy) were conducted. All animals maintained normal weight and health post-surgery. Results: Hemostasis was achieved at the laser incision site on the surgery day, but healing was slower compared to conventional methods. Micro-CT showed no significant differences in new bone formation or inflammatory tissue infiltration between groups. Tissue biopsy revealed slightly higher bone-implant contact in the FEMTO group compared to the SLA group, though not statistically significant. Conclusion: These findings suggest that femtosecond laser surface treatment may provide bone union comparable to or better than SLA treatment, though laser-assisted soft-tissue incisions heal more slowly.
format Article
id doaj-art-72d9313a71b14f03acbffff06e5a19c7
institution OA Journals
issn 2076-3417
language English
publishDate 2024-11-01
publisher MDPI AG
record_format Article
series Applied Sciences
spelling doaj-art-72d9313a71b14f03acbffff06e5a19c72025-08-20T01:55:27ZengMDPI AGApplied Sciences2076-34172024-11-0114231091310.3390/app142310913Bone Integration of Femtosecond Laser-Treated Dental Implants with Nanostructured Surfaces: A Controlled Animal StudyWoo-Seok Do0Keun-Ba-Da Son1Young-Tak Son2Yong-Gun Kim3Sung-Min Hwang4Jun-Ho Hwang5Jong-Hoon Lee6Hyun-Deok Kim7Kyu-Bok Lee8Jae-Mok Lee9Department of Periodontology, School of Dentistry, Kyungpook National University, Daegu 41940, Republic of KoreaAdvanced Dental Device Development Institute (A3DI), Kyungpook National University, Daegu 41940, Republic of KoreaAdvanced Dental Device Development Institute (A3DI), Kyungpook National University, Daegu 41940, Republic of KoreaDepartment of Periodontology, School of Dentistry, Kyungpook National University, Daegu 41940, Republic of KoreaDepartment of Periodontology, School of Dentistry, Kyungpook National University, Daegu 41940, Republic of KoreaInstitute of Advanced Convergence Technology, Kyungpook National University, Daegu 41061, Republic of KoreaInstitute of Advanced Convergence Technology, Kyungpook National University, Daegu 41061, Republic of KoreaSchool of Electronics Engineering, Kyungpook National University, Daegu 41566, Republic of KoreaDepartment of Prosthodontics, School of Dentistry, Kyungpook National University, Daegu 41940, Republic of KoreaDepartment of Periodontology, School of Dentistry, Kyungpook National University, Daegu 41940, Republic of KoreaBackground: The purpose of this study is to compare bone union and soft-tissue healing in titanium implants with sandblasted, large-grit, acid-etched surfaces (SLA group) and femtosecond laser-treated surfaces (FEMTO group) in a rabbit model. Methods: Implants were inserted into rabbit tibiae, and implant stability, soft-tissue healing, and microscopic analyses (micro-CT and biopsy) were conducted. All animals maintained normal weight and health post-surgery. Results: Hemostasis was achieved at the laser incision site on the surgery day, but healing was slower compared to conventional methods. Micro-CT showed no significant differences in new bone formation or inflammatory tissue infiltration between groups. Tissue biopsy revealed slightly higher bone-implant contact in the FEMTO group compared to the SLA group, though not statistically significant. Conclusion: These findings suggest that femtosecond laser surface treatment may provide bone union comparable to or better than SLA treatment, though laser-assisted soft-tissue incisions heal more slowly.https://www.mdpi.com/2076-3417/14/23/10913dental implantsdental lasersfemtosecond laserosseointegrationtitanium surface engineering
spellingShingle Woo-Seok Do
Keun-Ba-Da Son
Young-Tak Son
Yong-Gun Kim
Sung-Min Hwang
Jun-Ho Hwang
Jong-Hoon Lee
Hyun-Deok Kim
Kyu-Bok Lee
Jae-Mok Lee
Bone Integration of Femtosecond Laser-Treated Dental Implants with Nanostructured Surfaces: A Controlled Animal Study
Applied Sciences
dental implants
dental lasers
femtosecond laser
osseointegration
titanium surface engineering
title Bone Integration of Femtosecond Laser-Treated Dental Implants with Nanostructured Surfaces: A Controlled Animal Study
title_full Bone Integration of Femtosecond Laser-Treated Dental Implants with Nanostructured Surfaces: A Controlled Animal Study
title_fullStr Bone Integration of Femtosecond Laser-Treated Dental Implants with Nanostructured Surfaces: A Controlled Animal Study
title_full_unstemmed Bone Integration of Femtosecond Laser-Treated Dental Implants with Nanostructured Surfaces: A Controlled Animal Study
title_short Bone Integration of Femtosecond Laser-Treated Dental Implants with Nanostructured Surfaces: A Controlled Animal Study
title_sort bone integration of femtosecond laser treated dental implants with nanostructured surfaces a controlled animal study
topic dental implants
dental lasers
femtosecond laser
osseointegration
titanium surface engineering
url https://www.mdpi.com/2076-3417/14/23/10913
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