Radiation Recall Dermatitis following Radioactive Iodine Therapy: A New Observation

A 47-year-old female, who had previously received adjuvant right breast radiation for ductal carcinoma in situ, presented with right breast edema, erythema, and pain. This developed about two and a half weeks following radioactive iodine therapy for thyroid carcinoma. A biopsy was performed to rule...

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Main Authors: Ikechukwu Chidobem, Tahereh Orouji Jokar, Chisom Mgbodile, Francis Mgbodile, Ghassan Bassil, Nazia Khan
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2021/8422748
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author Ikechukwu Chidobem
Tahereh Orouji Jokar
Chisom Mgbodile
Francis Mgbodile
Ghassan Bassil
Nazia Khan
author_facet Ikechukwu Chidobem
Tahereh Orouji Jokar
Chisom Mgbodile
Francis Mgbodile
Ghassan Bassil
Nazia Khan
author_sort Ikechukwu Chidobem
collection DOAJ
description A 47-year-old female, who had previously received adjuvant right breast radiation for ductal carcinoma in situ, presented with right breast edema, erythema, and pain. This developed about two and a half weeks following radioactive iodine therapy for thyroid carcinoma. A biopsy was performed to rule out malignancy, since inflammatory breast cancer can present with similar symptoms. This confirmed radiation recall dermatitis (RRD) as the most likely diagnosis. RRD is an inflammatory reaction occurring in a previously irradiated field and was first described in 1959. Subsequent reports in the literature have associated it with the administration of other drugs, mostly chemotherapy. To our knowledge, this is the first reported case of RRD following radioactive iodine therapy.
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institution Kabale University
issn 2090-6706
2090-6714
language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series Case Reports in Oncological Medicine
spelling doaj-art-72d4a4d4006c4d84a9bed1968649571d2025-02-03T05:44:45ZengWileyCase Reports in Oncological Medicine2090-67062090-67142021-01-01202110.1155/2021/84227488422748Radiation Recall Dermatitis following Radioactive Iodine Therapy: A New ObservationIkechukwu Chidobem0Tahereh Orouji Jokar1Chisom Mgbodile2Francis Mgbodile3Ghassan Bassil4Nazia Khan5St. Mary’s General Hospital, Passaic, NJ, USASt. Mary’s General Hospital, Passaic, NJ, USASt. Mary’s General Hospital, Passaic, NJ, USASt. Mary’s General Hospital, Passaic, NJ, USASt. Mary’s General Hospital, Passaic, NJ, USASt. Mary’s General Hospital, Passaic, NJ, USAA 47-year-old female, who had previously received adjuvant right breast radiation for ductal carcinoma in situ, presented with right breast edema, erythema, and pain. This developed about two and a half weeks following radioactive iodine therapy for thyroid carcinoma. A biopsy was performed to rule out malignancy, since inflammatory breast cancer can present with similar symptoms. This confirmed radiation recall dermatitis (RRD) as the most likely diagnosis. RRD is an inflammatory reaction occurring in a previously irradiated field and was first described in 1959. Subsequent reports in the literature have associated it with the administration of other drugs, mostly chemotherapy. To our knowledge, this is the first reported case of RRD following radioactive iodine therapy.http://dx.doi.org/10.1155/2021/8422748
spellingShingle Ikechukwu Chidobem
Tahereh Orouji Jokar
Chisom Mgbodile
Francis Mgbodile
Ghassan Bassil
Nazia Khan
Radiation Recall Dermatitis following Radioactive Iodine Therapy: A New Observation
Case Reports in Oncological Medicine
title Radiation Recall Dermatitis following Radioactive Iodine Therapy: A New Observation
title_full Radiation Recall Dermatitis following Radioactive Iodine Therapy: A New Observation
title_fullStr Radiation Recall Dermatitis following Radioactive Iodine Therapy: A New Observation
title_full_unstemmed Radiation Recall Dermatitis following Radioactive Iodine Therapy: A New Observation
title_short Radiation Recall Dermatitis following Radioactive Iodine Therapy: A New Observation
title_sort radiation recall dermatitis following radioactive iodine therapy a new observation
url http://dx.doi.org/10.1155/2021/8422748
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AT chisommgbodile radiationrecalldermatitisfollowingradioactiveiodinetherapyanewobservation
AT francismgbodile radiationrecalldermatitisfollowingradioactiveiodinetherapyanewobservation
AT ghassanbassil radiationrecalldermatitisfollowingradioactiveiodinetherapyanewobservation
AT naziakhan radiationrecalldermatitisfollowingradioactiveiodinetherapyanewobservation