The Temporal Signature of Memories: Identification of a General Mechanism for Dynamic Memory Replay in Humans.
Reinstatement of dynamic memories requires the replay of neural patterns that unfold over time in a similar manner as during perception. However, little is known about the mechanisms that guide such a temporally structured replay in humans, because previous studies used either unsuitable methods or...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2016-08-01
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| Series: | PLoS Biology |
| Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1002528&type=printable |
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| _version_ | 1850130931030949888 |
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| author | Sebastian Michelmann Howard Bowman Simon Hanslmayr |
| author_facet | Sebastian Michelmann Howard Bowman Simon Hanslmayr |
| author_sort | Sebastian Michelmann |
| collection | DOAJ |
| description | Reinstatement of dynamic memories requires the replay of neural patterns that unfold over time in a similar manner as during perception. However, little is known about the mechanisms that guide such a temporally structured replay in humans, because previous studies used either unsuitable methods or paradigms to address this question. Here, we overcome these limitations by developing a new analysis method to detect the replay of temporal patterns in a paradigm that requires participants to mentally replay short sound or video clips. We show that memory reinstatement is accompanied by a decrease of low-frequency (8 Hz) power, which carries a temporal phase signature of the replayed stimulus. These replay effects were evident in the visual as well as in the auditory domain and were localized to sensory-specific regions. These results suggest low-frequency phase to be a domain-general mechanism that orchestrates dynamic memory replay in humans. |
| format | Article |
| id | doaj-art-72d0a919d0164495a5d7bb5053d418a2 |
| institution | OA Journals |
| issn | 1544-9173 1545-7885 |
| language | English |
| publishDate | 2016-08-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Biology |
| spelling | doaj-art-72d0a919d0164495a5d7bb5053d418a22025-08-20T02:32:33ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852016-08-01148e100252810.1371/journal.pbio.1002528The Temporal Signature of Memories: Identification of a General Mechanism for Dynamic Memory Replay in Humans.Sebastian MichelmannHoward BowmanSimon HanslmayrReinstatement of dynamic memories requires the replay of neural patterns that unfold over time in a similar manner as during perception. However, little is known about the mechanisms that guide such a temporally structured replay in humans, because previous studies used either unsuitable methods or paradigms to address this question. Here, we overcome these limitations by developing a new analysis method to detect the replay of temporal patterns in a paradigm that requires participants to mentally replay short sound or video clips. We show that memory reinstatement is accompanied by a decrease of low-frequency (8 Hz) power, which carries a temporal phase signature of the replayed stimulus. These replay effects were evident in the visual as well as in the auditory domain and were localized to sensory-specific regions. These results suggest low-frequency phase to be a domain-general mechanism that orchestrates dynamic memory replay in humans.https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1002528&type=printable |
| spellingShingle | Sebastian Michelmann Howard Bowman Simon Hanslmayr The Temporal Signature of Memories: Identification of a General Mechanism for Dynamic Memory Replay in Humans. PLoS Biology |
| title | The Temporal Signature of Memories: Identification of a General Mechanism for Dynamic Memory Replay in Humans. |
| title_full | The Temporal Signature of Memories: Identification of a General Mechanism for Dynamic Memory Replay in Humans. |
| title_fullStr | The Temporal Signature of Memories: Identification of a General Mechanism for Dynamic Memory Replay in Humans. |
| title_full_unstemmed | The Temporal Signature of Memories: Identification of a General Mechanism for Dynamic Memory Replay in Humans. |
| title_short | The Temporal Signature of Memories: Identification of a General Mechanism for Dynamic Memory Replay in Humans. |
| title_sort | temporal signature of memories identification of a general mechanism for dynamic memory replay in humans |
| url | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1002528&type=printable |
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