Adherence to diabetes risk reduction diet is associated with metabolic health status in adolescents with overweight or obesity
Abstract Background Insufficient evidence exists regarding the relationship between diabetes risk reduction diet (DRRD) and metabolic health status in adolescents. The current study aimed to investigate the relationship between DRRD and metabolic health status in Iranian adolescents with overweight/...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
|
| Series: | Nutrition Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12937-025-01111-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850039501041172480 |
|---|---|
| author | Ani Grigorian Zahra Moradmand Saeideh Mirzaei Ali Asadi Masoumeh Akhlaghi Parvane Saneei |
| author_facet | Ani Grigorian Zahra Moradmand Saeideh Mirzaei Ali Asadi Masoumeh Akhlaghi Parvane Saneei |
| author_sort | Ani Grigorian |
| collection | DOAJ |
| description | Abstract Background Insufficient evidence exists regarding the relationship between diabetes risk reduction diet (DRRD) and metabolic health status in adolescents. The current study aimed to investigate the relationship between DRRD and metabolic health status in Iranian adolescents with overweight/obesity. Methods In this cross-sectional study, a multistage cluster random sampling method was used to select 203 overweight/obese adolescents. Dietary intakes were evaluated using a validated 147-item food frequency questionnaire. The following parameters were measured: blood pressure, anthropometric indices, fasting glucose, insulin, and lipid profiles. Participants were classified to metabolically healthy overweight/obese (MHO) or metabolically unhealthy overweight/obese (MUO), based on 2 methods: International Diabetes Federation (IDF) criteria and a combination of IDF and Homeostasis Model Assessment Insulin Resistance (HOMA-IR). Results Based on IDF criteria, highest vs. lowest adherence to DRRD was associated with a lower odds of having an MUO phenotype in both crude (OR = 0.05; 95%CI: 0.02–0.12) and fully adjusted model (OR = 0.06; 95%CI: 0.02–0.20). Based on IDF/HOMA-IR criteria, similar findings were obtained. This relationship was significant in both genders and was especially significant among adolescents with obesity. In both crude and fully adjusted model, adherence to DRRD was significantly lower the likelihood of having high fasting blood glucose, triglycerides, and HOMA-IR. Conclusion Adolescents who adhered more strictly to DRRD were less likely to be MUO, and have high fasting blood glucose, triglycerides, and HOMA-IR. Additional large-scale prospective studies are necessary to affirm these results. |
| format | Article |
| id | doaj-art-72d06b2e1bfc4b9fa985cc9c19add821 |
| institution | DOAJ |
| issn | 1475-2891 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Nutrition Journal |
| spelling | doaj-art-72d06b2e1bfc4b9fa985cc9c19add8212025-08-20T02:56:20ZengBMCNutrition Journal1475-28912025-03-0124111010.1186/s12937-025-01111-xAdherence to diabetes risk reduction diet is associated with metabolic health status in adolescents with overweight or obesityAni Grigorian0Zahra Moradmand1Saeideh Mirzaei2Ali Asadi3Masoumeh Akhlaghi4Parvane Saneei5Students’ Research Committee, Isfahan University of Medical SciencesStudents’ Research Committee, Isfahan University of Medical SciencesDepartment of Community Nutrition, School of Nutrition and Food Science, Shiraz University of Medical SciencesDepartment of Exercise Physiology, School of Physical Education and Sport Sciences, University of TehranDepartment of Community Nutrition, School of Nutrition and Food Science, Shiraz University of Medical SciencesDepartment of Community Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Isfahan University of Medical SciencesAbstract Background Insufficient evidence exists regarding the relationship between diabetes risk reduction diet (DRRD) and metabolic health status in adolescents. The current study aimed to investigate the relationship between DRRD and metabolic health status in Iranian adolescents with overweight/obesity. Methods In this cross-sectional study, a multistage cluster random sampling method was used to select 203 overweight/obese adolescents. Dietary intakes were evaluated using a validated 147-item food frequency questionnaire. The following parameters were measured: blood pressure, anthropometric indices, fasting glucose, insulin, and lipid profiles. Participants were classified to metabolically healthy overweight/obese (MHO) or metabolically unhealthy overweight/obese (MUO), based on 2 methods: International Diabetes Federation (IDF) criteria and a combination of IDF and Homeostasis Model Assessment Insulin Resistance (HOMA-IR). Results Based on IDF criteria, highest vs. lowest adherence to DRRD was associated with a lower odds of having an MUO phenotype in both crude (OR = 0.05; 95%CI: 0.02–0.12) and fully adjusted model (OR = 0.06; 95%CI: 0.02–0.20). Based on IDF/HOMA-IR criteria, similar findings were obtained. This relationship was significant in both genders and was especially significant among adolescents with obesity. In both crude and fully adjusted model, adherence to DRRD was significantly lower the likelihood of having high fasting blood glucose, triglycerides, and HOMA-IR. Conclusion Adolescents who adhered more strictly to DRRD were less likely to be MUO, and have high fasting blood glucose, triglycerides, and HOMA-IR. Additional large-scale prospective studies are necessary to affirm these results.https://doi.org/10.1186/s12937-025-01111-xDiabetes risk reduction dietMetabolic health statusObesityOverweightAdolescents |
| spellingShingle | Ani Grigorian Zahra Moradmand Saeideh Mirzaei Ali Asadi Masoumeh Akhlaghi Parvane Saneei Adherence to diabetes risk reduction diet is associated with metabolic health status in adolescents with overweight or obesity Nutrition Journal Diabetes risk reduction diet Metabolic health status Obesity Overweight Adolescents |
| title | Adherence to diabetes risk reduction diet is associated with metabolic health status in adolescents with overweight or obesity |
| title_full | Adherence to diabetes risk reduction diet is associated with metabolic health status in adolescents with overweight or obesity |
| title_fullStr | Adherence to diabetes risk reduction diet is associated with metabolic health status in adolescents with overweight or obesity |
| title_full_unstemmed | Adherence to diabetes risk reduction diet is associated with metabolic health status in adolescents with overweight or obesity |
| title_short | Adherence to diabetes risk reduction diet is associated with metabolic health status in adolescents with overweight or obesity |
| title_sort | adherence to diabetes risk reduction diet is associated with metabolic health status in adolescents with overweight or obesity |
| topic | Diabetes risk reduction diet Metabolic health status Obesity Overweight Adolescents |
| url | https://doi.org/10.1186/s12937-025-01111-x |
| work_keys_str_mv | AT anigrigorian adherencetodiabetesriskreductiondietisassociatedwithmetabolichealthstatusinadolescentswithoverweightorobesity AT zahramoradmand adherencetodiabetesriskreductiondietisassociatedwithmetabolichealthstatusinadolescentswithoverweightorobesity AT saeidehmirzaei adherencetodiabetesriskreductiondietisassociatedwithmetabolichealthstatusinadolescentswithoverweightorobesity AT aliasadi adherencetodiabetesriskreductiondietisassociatedwithmetabolichealthstatusinadolescentswithoverweightorobesity AT masoumehakhlaghi adherencetodiabetesriskreductiondietisassociatedwithmetabolichealthstatusinadolescentswithoverweightorobesity AT parvanesaneei adherencetodiabetesriskreductiondietisassociatedwithmetabolichealthstatusinadolescentswithoverweightorobesity |