The TG/HDL-C Ratio Might Be a Surrogate for Insulin Resistance in Chinese Nonobese Women
Obejective. To examine the discriminatory power of triglyceride (TG) and triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) for insulin resistance (IR) in a normoglycaemic Chinese population. Methods. The data were collected from 711 individuals. The normoglycaemic individuals wer...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2014/105168 |
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| author | Jiyun He Sen He Kai Liu Yong Wang Di Shi Xiaoping Chen |
| author_facet | Jiyun He Sen He Kai Liu Yong Wang Di Shi Xiaoping Chen |
| author_sort | Jiyun He |
| collection | DOAJ |
| description | Obejective. To examine the discriminatory power of triglyceride (TG) and triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) for insulin resistance (IR) in a normoglycaemic Chinese population. Methods. The data were collected from 711 individuals. The normoglycaemic individuals were eventually included in the study (n = 533, age: 62.8 ± 6.6 years, male: 56.8%), who were with a fasting plasma glucose < 6.1 mmol/L and without a history of diabetes. IR was defined as the upper quintile (≥1.6) of homeostasis model assessment of IR. Area under the receiver operating characteristic curve (AROC) was used to examine the discriminatory power. Results. The discriminatory power of TG/HDL-C for IR was acceptable in women with a BMI < 24 kg/m2 or waist circumference < 80 cm (AROCs: 0.718 and 0.713, resp.); however, the discriminatory power was not acceptable in the obese women. TG/HDL-C was not an acceptable marker of IR in men. The discriminatory power of TG for IR was not acceptable in both men and women. Conclusions. The discriminatory power of TG/HDL-C for IR differs by gender and obesity index in the normoglycaemic Chinese population, and TG/HDL-C could discriminate IR in the nonobese and normoglycaemic women. |
| format | Article |
| id | doaj-art-72cbd1cf30a542349b9b764f910ebd34 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-72cbd1cf30a542349b9b764f910ebd342025-08-20T03:33:46ZengWileyInternational Journal of Endocrinology1687-83371687-83452014-01-01201410.1155/2014/105168105168The TG/HDL-C Ratio Might Be a Surrogate for Insulin Resistance in Chinese Nonobese WomenJiyun He0Sen He1Kai Liu2Yong Wang3Di Shi4Xiaoping Chen5Department of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu 610041, ChinaObejective. To examine the discriminatory power of triglyceride (TG) and triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) for insulin resistance (IR) in a normoglycaemic Chinese population. Methods. The data were collected from 711 individuals. The normoglycaemic individuals were eventually included in the study (n = 533, age: 62.8 ± 6.6 years, male: 56.8%), who were with a fasting plasma glucose < 6.1 mmol/L and without a history of diabetes. IR was defined as the upper quintile (≥1.6) of homeostasis model assessment of IR. Area under the receiver operating characteristic curve (AROC) was used to examine the discriminatory power. Results. The discriminatory power of TG/HDL-C for IR was acceptable in women with a BMI < 24 kg/m2 or waist circumference < 80 cm (AROCs: 0.718 and 0.713, resp.); however, the discriminatory power was not acceptable in the obese women. TG/HDL-C was not an acceptable marker of IR in men. The discriminatory power of TG for IR was not acceptable in both men and women. Conclusions. The discriminatory power of TG/HDL-C for IR differs by gender and obesity index in the normoglycaemic Chinese population, and TG/HDL-C could discriminate IR in the nonobese and normoglycaemic women.http://dx.doi.org/10.1155/2014/105168 |
| spellingShingle | Jiyun He Sen He Kai Liu Yong Wang Di Shi Xiaoping Chen The TG/HDL-C Ratio Might Be a Surrogate for Insulin Resistance in Chinese Nonobese Women International Journal of Endocrinology |
| title | The TG/HDL-C Ratio Might Be a Surrogate for Insulin Resistance in Chinese Nonobese Women |
| title_full | The TG/HDL-C Ratio Might Be a Surrogate for Insulin Resistance in Chinese Nonobese Women |
| title_fullStr | The TG/HDL-C Ratio Might Be a Surrogate for Insulin Resistance in Chinese Nonobese Women |
| title_full_unstemmed | The TG/HDL-C Ratio Might Be a Surrogate for Insulin Resistance in Chinese Nonobese Women |
| title_short | The TG/HDL-C Ratio Might Be a Surrogate for Insulin Resistance in Chinese Nonobese Women |
| title_sort | tg hdl c ratio might be a surrogate for insulin resistance in chinese nonobese women |
| url | http://dx.doi.org/10.1155/2014/105168 |
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