Aminoglycoside-induced hearing deficits – a review of cochlear ototoxicity

This article aims to inform the reader about current knowledge of the effects of aminoglycosides on hearing. The hearing loss caused by aminoglycosides is permanent and can negatively affect the individual’s quality of life. Although treatment with aminoglycosides cannot be avoided in some instances...

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Main Authors: Lucretia Petersen, Christine Rogers
Format: Article
Language:English
Published: AOSIS 2015-04-01
Series:South African Family Practice
Subjects:
Online Access:https://safpj.co.za/index.php/safpj/article/view/4153
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author Lucretia Petersen
Christine Rogers
author_facet Lucretia Petersen
Christine Rogers
author_sort Lucretia Petersen
collection DOAJ
description This article aims to inform the reader about current knowledge of the effects of aminoglycosides on hearing. The hearing loss caused by aminoglycosides is permanent and can negatively affect the individual’s quality of life. Although treatment with aminoglycosides cannot be avoided in some instances, timely intervention can minimise the impact of the hearing loss on the individual’s everyday life. The discussion includes the incidence of aminoglycoside-induced hearing loss and predisposing factors. In addition, monitoring and management of cochlear ototoxicity is described. (Full text available online at www.medpharm.tandfonline.com/ojfp) S Afr Fam Pract 2015; DOI: 10.1080/20786190.2014.1002220
format Article
id doaj-art-72c34cbdf931473e97e05b39647c2eda
institution Kabale University
issn 2078-6190
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language English
publishDate 2015-04-01
publisher AOSIS
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series South African Family Practice
spelling doaj-art-72c34cbdf931473e97e05b39647c2eda2025-08-20T03:47:09ZengAOSISSouth African Family Practice2078-61902078-62042015-04-0157210.4102/safp.v57i2.41534905Aminoglycoside-induced hearing deficits – a review of cochlear ototoxicityLucretia Petersen0Christine Rogers1University of Cape TownUniversity of Cape TownThis article aims to inform the reader about current knowledge of the effects of aminoglycosides on hearing. The hearing loss caused by aminoglycosides is permanent and can negatively affect the individual’s quality of life. Although treatment with aminoglycosides cannot be avoided in some instances, timely intervention can minimise the impact of the hearing loss on the individual’s everyday life. The discussion includes the incidence of aminoglycoside-induced hearing loss and predisposing factors. In addition, monitoring and management of cochlear ototoxicity is described. (Full text available online at www.medpharm.tandfonline.com/ojfp) S Afr Fam Pract 2015; DOI: 10.1080/20786190.2014.1002220https://safpj.co.za/index.php/safpj/article/view/4153amikacinaminoglycosidescochleotoxicityhearing losskanamycinototoxicity
spellingShingle Lucretia Petersen
Christine Rogers
Aminoglycoside-induced hearing deficits – a review of cochlear ototoxicity
South African Family Practice
amikacin
aminoglycosides
cochleotoxicity
hearing loss
kanamycin
ototoxicity
title Aminoglycoside-induced hearing deficits – a review of cochlear ototoxicity
title_full Aminoglycoside-induced hearing deficits – a review of cochlear ototoxicity
title_fullStr Aminoglycoside-induced hearing deficits – a review of cochlear ototoxicity
title_full_unstemmed Aminoglycoside-induced hearing deficits – a review of cochlear ototoxicity
title_short Aminoglycoside-induced hearing deficits – a review of cochlear ototoxicity
title_sort aminoglycoside induced hearing deficits a review of cochlear ototoxicity
topic amikacin
aminoglycosides
cochleotoxicity
hearing loss
kanamycin
ototoxicity
url https://safpj.co.za/index.php/safpj/article/view/4153
work_keys_str_mv AT lucretiapetersen aminoglycosideinducedhearingdeficitsareviewofcochlearototoxicity
AT christinerogers aminoglycosideinducedhearingdeficitsareviewofcochlearototoxicity