Immunotherapy for rapid bone marrow conditioning and leukemia depletion that allows efficient hematopoietic stem cell transplantation

Immunotherapy for rapid bone marrow conditioning and leukemia depletion that allows efficient hematopoietic stem cell transplantation

Hematopoietic stem cell transplantation (HSCT) is a life-saving procedure to treat hematopoietic disorders. Current bone marrow conditioning protocols create space for healthy donor stem cells by employing irradiation and/or chemotherapy, but carry severe toxicities, resulting in significant morbidi...

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Main Authors: Yun He, Yuandong Wang, Yvonne M Mueller, Peter D Katsikis, Jiuqiao Zhao, Jan J Cornelissen, Marc H G P Raaijmakers, Vincent H J van der Velden, Stefan J Erkeland, Giada Dal Collo, Srdjan Grusanovic, Milad Rasouli, Antoinette van Hoven-Beijen, Zara-Li van der Sande, Martin van Hagen, Emma De Pater, Meritxell Alberich-Jorda
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/6/e011888.full
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