High glucose condition aggravates inflammatory response induced by Porphyromonas gingivalis in THP-1 macrophages via autophagy inhibition

High glucose condition aggravates inflammatory response induced by Porphyromonas gingivalis in THP-1 macrophages via autophagy inhibition

Abstract Background Porphyromonase gingivalis (P. gingivalis) is a type of bacteria that causes periodontitis, which is strongly correlated with systemic diseases such as diabetes. However, the effect of hyperglycemia on periodontitis are unclear. The present study examined the effects of high gluco...

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Bibliographic Details
Main Authors: Yuri Song, Jin-Ju Kwon, Hee Sam Na, Si Yeong Kim, Sang-Hun Shin, Jin Chung
Format: Article
Language:English
Published: BMC 2024-10-01
Series:BMC Immunology
Subjects:
Autophagy
Hyperglycaemia
Inflammation
Periodontitis
Porphyromonase gingivalis
Online Access:https://doi.org/10.1186/s12865-024-00655-7
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