Dynamics of neutrophil phenotype and function in sickle cell disease

IntroductionWhile sickle cell disease (SCD) is primarily acknowledged as an erythrocyte disorder, emerging evidence suggests a role for altered neutrophil phenotype and function in SCD pathophysiology and disease severity. Given the conflicting findings in previous studies, we performed a comprehens...

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Bibliographic Details
Main Authors:	Aafke E. Gaartman, Lydian A. de Ligt, Boukje M. Beuger, Anton T. J. Tool, Martijn Veldthuis, Taco W. Kuijpers, Rob van Zwieten, Bart J. Biemond, Robin van Bruggen, Erfan Nur
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Immunology
Subjects:	sickle cell disease neutrophil activation neutrophil adhesion neutrohil aging neutrophil phenotype hemolysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1591283/full
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Dynamics of neutrophil phenotype and function in sickle cell disease

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