Topical Treatment with Cord Blood Serum in Glaucoma Patients: A Preliminary Report

Purpose. To report data which happened to be observed in two glaucoma patients treated with Cord Blood Serum (CBS) eye drops. Design. A case report and retrospective data analysis. Methods. CBS topical eye drops, characterized in advance for growth factors (GFs) content, were administered for two mo...

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Main Authors: Emilio Campos, Piera Versura, Giuseppe Giannaccare, Adriana Terzi, Silvia Bisti, Stefano Di Marco, Marina Buzzi
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2018/2381296
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author Emilio Campos
Piera Versura
Giuseppe Giannaccare
Adriana Terzi
Silvia Bisti
Stefano Di Marco
Marina Buzzi
author_facet Emilio Campos
Piera Versura
Giuseppe Giannaccare
Adriana Terzi
Silvia Bisti
Stefano Di Marco
Marina Buzzi
author_sort Emilio Campos
collection DOAJ
description Purpose. To report data which happened to be observed in two glaucoma patients treated with Cord Blood Serum (CBS) eye drops. Design. A case report and retrospective data analysis. Methods. CBS topical eye drops, characterized in advance for growth factors (GFs) content, were administered for two months with the aim to relieve their subjective symptoms, in two patients who had referred ocular surface discomfort, although in absence of any sign of keratopathy. As patients were also affected by advanced glaucoma at risk of vision loss and under treatment with hypotensive drugs, they had been also monitored over the same period with IOP controls and visual field tests in our unit. Results. During subsequent visits, data from Mean Deviation and Pattern Standard Deviation in the visual fields were retrospectively collected and compared with before and after treatment with CBS, and an amelioration was observed. Conclusions. CBS contains a combination of GFs, which potentially exert a neuroprotective action and elect CBS as an interesting natural source to be delivered in neurodegenerative ocular disorders. The incidentally observed amelioration in these two patients deserves further investigation in this respect.
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-72ae0f38fd024e4fa47c28c2f870ea0c2025-08-20T02:06:26ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302018-01-01201810.1155/2018/23812962381296Topical Treatment with Cord Blood Serum in Glaucoma Patients: A Preliminary ReportEmilio Campos0Piera Versura1Giuseppe Giannaccare2Adriana Terzi3Silvia Bisti4Stefano Di Marco5Marina Buzzi6Ophthalmology Unit, DIMES, Alma Mater Studiorum, University of Bologna, Bologna, ItalyOphthalmology Unit, DIMES, Alma Mater Studiorum, University of Bologna, Bologna, ItalyOphthalmology Unit, DIMES, Alma Mater Studiorum, University of Bologna, Bologna, ItalyEmilia Romagna Cord Blood Bank-Transfusion Service, S.Orsola-Malpighi Teaching Hospital, Bologna, ItalyVision Lab, DISCAB, University of L’Aquila, L’Aquila, ItalyVision Lab, DISCAB, University of L’Aquila, L’Aquila, ItalyEmilia Romagna Cord Blood Bank-Transfusion Service, S.Orsola-Malpighi Teaching Hospital, Bologna, ItalyPurpose. To report data which happened to be observed in two glaucoma patients treated with Cord Blood Serum (CBS) eye drops. Design. A case report and retrospective data analysis. Methods. CBS topical eye drops, characterized in advance for growth factors (GFs) content, were administered for two months with the aim to relieve their subjective symptoms, in two patients who had referred ocular surface discomfort, although in absence of any sign of keratopathy. As patients were also affected by advanced glaucoma at risk of vision loss and under treatment with hypotensive drugs, they had been also monitored over the same period with IOP controls and visual field tests in our unit. Results. During subsequent visits, data from Mean Deviation and Pattern Standard Deviation in the visual fields were retrospectively collected and compared with before and after treatment with CBS, and an amelioration was observed. Conclusions. CBS contains a combination of GFs, which potentially exert a neuroprotective action and elect CBS as an interesting natural source to be delivered in neurodegenerative ocular disorders. The incidentally observed amelioration in these two patients deserves further investigation in this respect.http://dx.doi.org/10.1155/2018/2381296
spellingShingle Emilio Campos
Piera Versura
Giuseppe Giannaccare
Adriana Terzi
Silvia Bisti
Stefano Di Marco
Marina Buzzi
Topical Treatment with Cord Blood Serum in Glaucoma Patients: A Preliminary Report
Case Reports in Ophthalmological Medicine
title Topical Treatment with Cord Blood Serum in Glaucoma Patients: A Preliminary Report
title_full Topical Treatment with Cord Blood Serum in Glaucoma Patients: A Preliminary Report
title_fullStr Topical Treatment with Cord Blood Serum in Glaucoma Patients: A Preliminary Report
title_full_unstemmed Topical Treatment with Cord Blood Serum in Glaucoma Patients: A Preliminary Report
title_short Topical Treatment with Cord Blood Serum in Glaucoma Patients: A Preliminary Report
title_sort topical treatment with cord blood serum in glaucoma patients a preliminary report
url http://dx.doi.org/10.1155/2018/2381296
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AT adrianaterzi topicaltreatmentwithcordbloodseruminglaucomapatientsapreliminaryreport
AT silviabisti topicaltreatmentwithcordbloodseruminglaucomapatientsapreliminaryreport
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