Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review
Pharyngeal liposarcomas are very rare; still more rare are dedifferentiated liposarcomas in the pharynx. An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. A 3.5 cm mass was identified in the hypopharynx. The mass was biopsie...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2020/2968467 |
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| _version_ | 1849414736588832768 |
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| author | Peter Wanes David A. Nolte Ghassan A. Tranesh |
| author_facet | Peter Wanes David A. Nolte Ghassan A. Tranesh |
| author_sort | Peter Wanes |
| collection | DOAJ |
| description | Pharyngeal liposarcomas are very rare; still more rare are dedifferentiated liposarcomas in the pharynx. An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. A 3.5 cm mass was identified in the hypopharynx. The mass was biopsied and diagnosed as a benign fibroepithelial polyp. Continued symptoms and airway obstruction prompted a pharyngectomy, and the mass was then diagnosed as dedifferentiated liposarcoma. Due to infrequency and subtle histological findings, liposarcomas of the head and neck can be misdiagnosed and recur. |
| format | Article |
| id | doaj-art-72acf189c8ff4ec3a7d9261b7f823e30 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-72acf189c8ff4ec3a7d9261b7f823e302025-08-20T03:33:43ZengWileyCase Reports in Pathology2090-67812090-679X2020-01-01202010.1155/2020/29684672968467Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short ReviewPeter Wanes0David A. Nolte1Ghassan A. Tranesh2Department of Pathology, University of Arizona, 1501 N. Campbell Ave, Tucson, AZ 85724, USADepartment of Pathology, University of Arizona, 1501 N. Campbell Ave, Tucson, AZ 85724, USADepartment of Pathology, University of Arizona, 1501 N. Campbell Ave, Tucson, AZ 85724, USAPharyngeal liposarcomas are very rare; still more rare are dedifferentiated liposarcomas in the pharynx. An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. A 3.5 cm mass was identified in the hypopharynx. The mass was biopsied and diagnosed as a benign fibroepithelial polyp. Continued symptoms and airway obstruction prompted a pharyngectomy, and the mass was then diagnosed as dedifferentiated liposarcoma. Due to infrequency and subtle histological findings, liposarcomas of the head and neck can be misdiagnosed and recur.http://dx.doi.org/10.1155/2020/2968467 |
| spellingShingle | Peter Wanes David A. Nolte Ghassan A. Tranesh Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review Case Reports in Pathology |
| title | Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review |
| title_full | Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review |
| title_fullStr | Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review |
| title_full_unstemmed | Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review |
| title_short | Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review |
| title_sort | hypopharyngeal dedifferentiated liposarcoma in the mdm2 era a case report and short review |
| url | http://dx.doi.org/10.1155/2020/2968467 |
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