Testing the reproducibility of ecological studies on insect behavior in a multi-laboratory setting identifies opportunities for improving experimental rigor.

The reproducibility of studies involving insect species is an underexplored area in the broader discussion about poor reproducibility in science. Our study addresses this gap by conducting a systematic multi-laboratory investigation into the reproducibility of ecological studies on insect behavior....

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Main Authors: Carolin Mundinger, Nora K E Schulz, Pragya Singh, Steven Janz, Maximilian Schurig, Jacob Seidemann, Joachim Kurtz, Caroline Müller, Holger Schielzeth, Vanessa T von Kortzfleisch, S Helene Richter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-04-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3003019
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author Carolin Mundinger
Nora K E Schulz
Pragya Singh
Steven Janz
Maximilian Schurig
Jacob Seidemann
Joachim Kurtz
Caroline Müller
Holger Schielzeth
Vanessa T von Kortzfleisch
S Helene Richter
author_facet Carolin Mundinger
Nora K E Schulz
Pragya Singh
Steven Janz
Maximilian Schurig
Jacob Seidemann
Joachim Kurtz
Caroline Müller
Holger Schielzeth
Vanessa T von Kortzfleisch
S Helene Richter
author_sort Carolin Mundinger
collection DOAJ
description The reproducibility of studies involving insect species is an underexplored area in the broader discussion about poor reproducibility in science. Our study addresses this gap by conducting a systematic multi-laboratory investigation into the reproducibility of ecological studies on insect behavior. We implemented a 3 × 3 experimental design, incorporating three study sites, and three independent experiments on three insect species from different orders: the turnip sawfly (Athalia rosae, Hymenoptera), the meadow grasshopper (Pseudochorthippus parallelus, Orthoptera), and the red flour beetle (Tribolium castaneum, Coleoptera). Using random-effect meta-analysis, we compared the consistency and accuracy of treatment effects on insect behavioral traits across replicate experiments. We successfully reproduced the overall statistical treatment effect in 83% of the replicate experiments, but overall effect size replication was achieved in only 66% of the replicates. Thus, though demonstrating sufficient reproducibility in some measures, this study also provides the first experimental evidence for cases of poor reproducibility in insect experiments. Our findings further show that reasons causing poor reproducibility established in rodent research also hold for other study organisms and research questions. We believe that a rethinking of current best practices is required to face reproducibility issues in insect studies but also across disciplines. Specifically, we advocate for adopting open research practices and the implementation of methodological strategies that reduce bias and problems arising from over-standardization. With respect to the latter, the introduction of systematic variation through multi-laboratory or heterogenized designs may contribute to improved reproducibility in studies involving any living organisms.
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spelling doaj-art-72a51d3cc22947c5a6b0833f396ccae92025-08-20T03:14:40ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852025-04-01234e300301910.1371/journal.pbio.3003019Testing the reproducibility of ecological studies on insect behavior in a multi-laboratory setting identifies opportunities for improving experimental rigor.Carolin MundingerNora K E SchulzPragya SinghSteven JanzMaximilian SchurigJacob SeidemannJoachim KurtzCaroline MüllerHolger SchielzethVanessa T von KortzfleischS Helene RichterThe reproducibility of studies involving insect species is an underexplored area in the broader discussion about poor reproducibility in science. Our study addresses this gap by conducting a systematic multi-laboratory investigation into the reproducibility of ecological studies on insect behavior. We implemented a 3 × 3 experimental design, incorporating three study sites, and three independent experiments on three insect species from different orders: the turnip sawfly (Athalia rosae, Hymenoptera), the meadow grasshopper (Pseudochorthippus parallelus, Orthoptera), and the red flour beetle (Tribolium castaneum, Coleoptera). Using random-effect meta-analysis, we compared the consistency and accuracy of treatment effects on insect behavioral traits across replicate experiments. We successfully reproduced the overall statistical treatment effect in 83% of the replicate experiments, but overall effect size replication was achieved in only 66% of the replicates. Thus, though demonstrating sufficient reproducibility in some measures, this study also provides the first experimental evidence for cases of poor reproducibility in insect experiments. Our findings further show that reasons causing poor reproducibility established in rodent research also hold for other study organisms and research questions. We believe that a rethinking of current best practices is required to face reproducibility issues in insect studies but also across disciplines. Specifically, we advocate for adopting open research practices and the implementation of methodological strategies that reduce bias and problems arising from over-standardization. With respect to the latter, the introduction of systematic variation through multi-laboratory or heterogenized designs may contribute to improved reproducibility in studies involving any living organisms.https://doi.org/10.1371/journal.pbio.3003019
spellingShingle Carolin Mundinger
Nora K E Schulz
Pragya Singh
Steven Janz
Maximilian Schurig
Jacob Seidemann
Joachim Kurtz
Caroline Müller
Holger Schielzeth
Vanessa T von Kortzfleisch
S Helene Richter
Testing the reproducibility of ecological studies on insect behavior in a multi-laboratory setting identifies opportunities for improving experimental rigor.
PLoS Biology
title Testing the reproducibility of ecological studies on insect behavior in a multi-laboratory setting identifies opportunities for improving experimental rigor.
title_full Testing the reproducibility of ecological studies on insect behavior in a multi-laboratory setting identifies opportunities for improving experimental rigor.
title_fullStr Testing the reproducibility of ecological studies on insect behavior in a multi-laboratory setting identifies opportunities for improving experimental rigor.
title_full_unstemmed Testing the reproducibility of ecological studies on insect behavior in a multi-laboratory setting identifies opportunities for improving experimental rigor.
title_short Testing the reproducibility of ecological studies on insect behavior in a multi-laboratory setting identifies opportunities for improving experimental rigor.
title_sort testing the reproducibility of ecological studies on insect behavior in a multi laboratory setting identifies opportunities for improving experimental rigor
url https://doi.org/10.1371/journal.pbio.3003019
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