Research progress on the therapeutic effect and mechanism of Akkermansia Muciniphila on metabolic diseases
Metabolic diseases are a kind of chronic diseases caused by abnormal metabolism of matter or energy, including obesity, diabetes and non-alcoholic fatty liver disease, etc., which have seriously harmed people's health. Studies have shown that the imbalance of gut microbiota is closely related t...
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| Format: | Article |
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Editorial Office of Journal of Guangxi Medical University
2024-11-01
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| Series: | Guangxi Yike Daxue xuebao |
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| Online Access: | https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.11.009 |
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| author | CUI Xin ZHANG Yangyang CHEN Lina |
| author_facet | CUI Xin ZHANG Yangyang CHEN Lina |
| author_sort | CUI Xin |
| collection | DOAJ |
| description | Metabolic diseases are a kind of chronic diseases caused by abnormal metabolism of matter or energy, including obesity, diabetes and non-alcoholic fatty liver disease, etc., which have seriously harmed people's health. Studies have shown that the imbalance of gut microbiota is closely related to the occurrence and development of various metabolic diseases, and the regulation of gut microbiota may have positive significance in improving metabolic diseases. Akkermansia muciniphila is a new type of probiotic, which may have protective effects on metabolic diseases by repairing intestinal barrier, regulating gut microbiota and improving host metabolism. In order to provide theoretical basis for clinical treatment, this paper reviews the research progress on the therapeutic effect and mechanism of Akkermansia muciniphila on metabolic diseases, including obesity, diabetes and nonalcoholic fatty liver disease. |
| format | Article |
| id | doaj-art-72a103e2b3b24527b4606fca2ff1e029 |
| institution | DOAJ |
| issn | 1005-930X |
| language | zho |
| publishDate | 2024-11-01 |
| publisher | Editorial Office of Journal of Guangxi Medical University |
| record_format | Article |
| series | Guangxi Yike Daxue xuebao |
| spelling | doaj-art-72a103e2b3b24527b4606fca2ff1e0292025-08-20T02:57:36ZzhoEditorial Office of Journal of Guangxi Medical UniversityGuangxi Yike Daxue xuebao1005-930X2024-11-0141111501150610.16190/j.cnki.45-1211/r.2024.11.009gxykdxxb-41-11-1501Research progress on the therapeutic effect and mechanism of Akkermansia Muciniphila on metabolic diseasesCUI Xin0ZHANG Yangyang1CHEN Lina2Department of Pharmacology, School of Basic Medical Sciences, Xi' an Jiaotong University Health Science Center, Xi'an 710061, ChinaDepartment of Pharmacology, School of Basic Medical Sciences, Xi' an Jiaotong University Health Science Center, Xi'an 710061, ChinaDepartment of Pharmacology, School of Basic Medical Sciences, Xi' an Jiaotong University Health Science Center, Xi'an 710061, ChinaMetabolic diseases are a kind of chronic diseases caused by abnormal metabolism of matter or energy, including obesity, diabetes and non-alcoholic fatty liver disease, etc., which have seriously harmed people's health. Studies have shown that the imbalance of gut microbiota is closely related to the occurrence and development of various metabolic diseases, and the regulation of gut microbiota may have positive significance in improving metabolic diseases. Akkermansia muciniphila is a new type of probiotic, which may have protective effects on metabolic diseases by repairing intestinal barrier, regulating gut microbiota and improving host metabolism. In order to provide theoretical basis for clinical treatment, this paper reviews the research progress on the therapeutic effect and mechanism of Akkermansia muciniphila on metabolic diseases, including obesity, diabetes and nonalcoholic fatty liver disease.https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.11.009akkermansia muciniphilametabolic diseasesgut microbiota |
| spellingShingle | CUI Xin ZHANG Yangyang CHEN Lina Research progress on the therapeutic effect and mechanism of Akkermansia Muciniphila on metabolic diseases Guangxi Yike Daxue xuebao akkermansia muciniphila metabolic diseases gut microbiota |
| title | Research progress on the therapeutic effect and mechanism of Akkermansia Muciniphila on metabolic diseases |
| title_full | Research progress on the therapeutic effect and mechanism of Akkermansia Muciniphila on metabolic diseases |
| title_fullStr | Research progress on the therapeutic effect and mechanism of Akkermansia Muciniphila on metabolic diseases |
| title_full_unstemmed | Research progress on the therapeutic effect and mechanism of Akkermansia Muciniphila on metabolic diseases |
| title_short | Research progress on the therapeutic effect and mechanism of Akkermansia Muciniphila on metabolic diseases |
| title_sort | research progress on the therapeutic effect and mechanism of akkermansia muciniphila on metabolic diseases |
| topic | akkermansia muciniphila metabolic diseases gut microbiota |
| url | https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.11.009 |
| work_keys_str_mv | AT cuixin researchprogressonthetherapeuticeffectandmechanismofakkermansiamuciniphilaonmetabolicdiseases AT zhangyangyang researchprogressonthetherapeuticeffectandmechanismofakkermansiamuciniphilaonmetabolicdiseases AT chenlina researchprogressonthetherapeuticeffectandmechanismofakkermansiamuciniphilaonmetabolicdiseases |