Spatiotemporal Distribution and Clinical Characteristics of Zoonotic Tuberculosis, Spain, 2018–2022
Zoonotic tuberculosis (zTB) is a communicable disease that has major effects on both human and animal health. Spain reports the highest number of zTB cases in humans annually in the European Union. We describe the epidemiology of human cases of zTB caused by Mycobacterium bovis and M. caprae in Spa...
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2025-07-01
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| Series: | Emerging Infectious Diseases |
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| Online Access: | https://wwwnc.cdc.gov/eid/article/31/7/25-0031_article |
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| author | Álvaro Roy Diana Gómez-Barroso Elena Cruz-Ferro Ana Fernández Isabel Martínez-Pino María del Henar Marcos Isabel Ursúa-Díaz Susana Miras Nuria Echave Evi Ounarou Beatriz Romero Laura Herrera-León Zaida Herrador |
| author_facet | Álvaro Roy Diana Gómez-Barroso Elena Cruz-Ferro Ana Fernández Isabel Martínez-Pino María del Henar Marcos Isabel Ursúa-Díaz Susana Miras Nuria Echave Evi Ounarou Beatriz Romero Laura Herrera-León Zaida Herrador |
| author_sort | Álvaro Roy |
| collection | DOAJ |
| description |
Zoonotic tuberculosis (zTB) is a communicable disease that has major effects on both human and animal health. Spain reports the highest number of zTB cases in humans annually in the European Union. We describe the epidemiology of human cases of zTB caused by Mycobacterium bovis and M. caprae in Spain during 2018–2022. The incidence of M. bovis infection compared with M. tuberculosis infection was higher in patients who were native-born (adjusted odds ratio [aOR) 2.32, 95% CI 1.44–3.82), HIV-negative (aOR 3.39, 95% CI 1.24–14.0), or had extrapulmonary forms of TB (aOR 2.20, 95% CI 1.46–3.28). The spatial pattern differed by M. tuberculosis complex species; we identified 3 significant clusters of M. bovis and 1 of M. caprae in bovine TB–free regions. Our results show the importance of including animal and human data on circulating zoonotic pathogens under the One Health umbrella.
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| format | Article |
| id | doaj-art-7292aff0a1af425c99484ff89ebc42e4 |
| institution | Kabale University |
| issn | 1080-6040 1080-6059 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj-art-7292aff0a1af425c99484ff89ebc42e42025-08-20T03:29:44ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592025-07-013171344135210.3201/eid3107.250031Spatiotemporal Distribution and Clinical Characteristics of Zoonotic Tuberculosis, Spain, 2018–2022Álvaro RoyDiana Gómez-BarrosoElena Cruz-FerroAna FernándezIsabel Martínez-PinoMaría del Henar MarcosIsabel Ursúa-DíazSusana MirasNuria EchaveEvi OunarouBeatriz RomeroLaura Herrera-LeónZaida Herrador Zoonotic tuberculosis (zTB) is a communicable disease that has major effects on both human and animal health. Spain reports the highest number of zTB cases in humans annually in the European Union. We describe the epidemiology of human cases of zTB caused by Mycobacterium bovis and M. caprae in Spain during 2018–2022. The incidence of M. bovis infection compared with M. tuberculosis infection was higher in patients who were native-born (adjusted odds ratio [aOR) 2.32, 95% CI 1.44–3.82), HIV-negative (aOR 3.39, 95% CI 1.24–14.0), or had extrapulmonary forms of TB (aOR 2.20, 95% CI 1.46–3.28). The spatial pattern differed by M. tuberculosis complex species; we identified 3 significant clusters of M. bovis and 1 of M. caprae in bovine TB–free regions. Our results show the importance of including animal and human data on circulating zoonotic pathogens under the One Health umbrella. https://wwwnc.cdc.gov/eid/article/31/7/25-0031_articletuberculosis and other mycobacteriaMycobacterium bovisMycobacterium tuberculosisMycobacterium capraezoonotic tuberculosisOne Health |
| spellingShingle | Álvaro Roy Diana Gómez-Barroso Elena Cruz-Ferro Ana Fernández Isabel Martínez-Pino María del Henar Marcos Isabel Ursúa-Díaz Susana Miras Nuria Echave Evi Ounarou Beatriz Romero Laura Herrera-León Zaida Herrador Spatiotemporal Distribution and Clinical Characteristics of Zoonotic Tuberculosis, Spain, 2018–2022 Emerging Infectious Diseases tuberculosis and other mycobacteria Mycobacterium bovis Mycobacterium tuberculosis Mycobacterium caprae zoonotic tuberculosis One Health |
| title | Spatiotemporal Distribution and Clinical Characteristics of Zoonotic Tuberculosis, Spain, 2018–2022 |
| title_full | Spatiotemporal Distribution and Clinical Characteristics of Zoonotic Tuberculosis, Spain, 2018–2022 |
| title_fullStr | Spatiotemporal Distribution and Clinical Characteristics of Zoonotic Tuberculosis, Spain, 2018–2022 |
| title_full_unstemmed | Spatiotemporal Distribution and Clinical Characteristics of Zoonotic Tuberculosis, Spain, 2018–2022 |
| title_short | Spatiotemporal Distribution and Clinical Characteristics of Zoonotic Tuberculosis, Spain, 2018–2022 |
| title_sort | spatiotemporal distribution and clinical characteristics of zoonotic tuberculosis spain 2018 2022 |
| topic | tuberculosis and other mycobacteria Mycobacterium bovis Mycobacterium tuberculosis Mycobacterium caprae zoonotic tuberculosis One Health |
| url | https://wwwnc.cdc.gov/eid/article/31/7/25-0031_article |
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