HA198 mutations in H9N2 avian influenza: molecular dynamics insights into receptor binding

IntroductionThe H9N2 avian influenza virus is widely disseminated in poultry and poses a zoonotic threat, despite vaccination efforts. Mutations at residue 198 of hemagglutinin (HA) are critical for antigenic variation and receptor-binding specificity, but the underlying molecular mechanisms remain...

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Bibliographic Details
Main Authors:	Rui Zhu, Jie Wu, Ruiying Chen, Mo Zhou, Shinuo Cao, Zhi Wu, Ligang Wang, Lei Zhang, Shanyuan Zhu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Veterinary Science
Subjects:	H9N2 avian influenza virus mutations at residue 198 hemagglutinin receptor binding molecular dynamics simulations
Online Access:	https://www.frontiersin.org/articles/10.3389/fvets.2024.1526600/full
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HA198 mutations in H9N2 avian influenza: molecular dynamics insights into receptor binding

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