Single-cell RNA sequencing highlights a significant retinal Müller glial population in dry age-related macular degeneration

Single-cell RNA sequencing highlights a significant retinal Müller glial population in dry age-related macular degeneration

Summary: The main challenge in dissecting the cells and pathways involved in the pathogenesis of age-related macular degeneration (AMD) is the highly heterogeneous and dynamic nature of the retinal microenvironment. This study aimed to describe the comprehensive landscape of the dry AMD (dAMD) model...

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Bibliographic Details
Main Authors: Bing Zeng, Chuanhe Zhang, Yifan Liang, Jianguo Huang, Deshuang Li, Ziling Liu, Hongxia Liao, Tedu Yang, Muyun Liu, Chang Zou, Dongcheng Liu, Bo Qin
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
Subjects:
Pathophysiology
complex system biology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225007254
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