Non-IgE-mediated gastrointestinal food allergy in children. Diagnostics, differential diagnostics, tactics of diet therapy
In routine pediatric practice, non-IgE-mediated forms of gastrointestinal food allergy are still poorly recognized. This is due to the variety of clinical manifestations, the lack of reliable laboratory diagnostic methods, the unclear association with time, and the causal relationship with the aller...
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| Format: | Article |
| Language: | Russian |
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Open Systems Publication
2023-07-01
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| Series: | Лечащий Врач |
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| Online Access: | https://journal.lvrach.ru/jour/article/view/1081 |
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| author | S. G. Makarova T. E. Lavrova G. A. Novik |
| author_facet | S. G. Makarova T. E. Lavrova G. A. Novik |
| author_sort | S. G. Makarova |
| collection | DOAJ |
| description | In routine pediatric practice, non-IgE-mediated forms of gastrointestinal food allergy are still poorly recognized. This is due to the variety of clinical manifestations, the lack of reliable laboratory diagnostic methods, the unclear association with time, and the causal relationship with the allergen. Immature barrier mechanisms and early transition to formula feeding increase the penetration of allergen proteins, leading to sensitization. The article discusses three clinical forms of non-IgE-mediated gastrointestinal food allergy in children: food protein-induced enterocolitis syndrome, food protein enteropathy, and food protein-induced proctocolitis. In these cases, diet is a universal diagnostic and therapeutic measure. Eliminating the allergen allows for immunological reset and the induce the food tolerance. Therefore, strict adherence to elimination diets is crucial. The article also provides a differential diagnosis based on the level of allergic inflammation of the intestine and outlines principles and protocols for diagnostic and elimination diets. |
| format | Article |
| id | doaj-art-7285cd6f2dae40cb9875ba4e84ce21b2 |
| institution | Kabale University |
| issn | 1560-5175 2687-1181 |
| language | Russian |
| publishDate | 2023-07-01 |
| publisher | Open Systems Publication |
| record_format | Article |
| series | Лечащий Врач |
| spelling | doaj-art-7285cd6f2dae40cb9875ba4e84ce21b22025-08-20T03:37:06ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812023-07-0106202910.51793/OS.2023.26.6.0031075Non-IgE-mediated gastrointestinal food allergy in children. Diagnostics, differential diagnostics, tactics of diet therapyS. G. Makarova0T. E. Lavrova1G. A. Novik2Federal State Autonomous Institution National Medical Research Center for Children's Health of the Ministry of Health of the Russian FederationNutricia Limited Liability CompanyFederal State Budgetary Educational Institution of Higher Education St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian FederationIn routine pediatric practice, non-IgE-mediated forms of gastrointestinal food allergy are still poorly recognized. This is due to the variety of clinical manifestations, the lack of reliable laboratory diagnostic methods, the unclear association with time, and the causal relationship with the allergen. Immature barrier mechanisms and early transition to formula feeding increase the penetration of allergen proteins, leading to sensitization. The article discusses three clinical forms of non-IgE-mediated gastrointestinal food allergy in children: food protein-induced enterocolitis syndrome, food protein enteropathy, and food protein-induced proctocolitis. In these cases, diet is a universal diagnostic and therapeutic measure. Eliminating the allergen allows for immunological reset and the induce the food tolerance. Therefore, strict adherence to elimination diets is crucial. The article also provides a differential diagnosis based on the level of allergic inflammation of the intestine and outlines principles and protocols for diagnostic and elimination diets.https://journal.lvrach.ru/jour/article/view/1081food allergycow's milk proteinsdiagnosisdiet therapyenterocolitisproctocolitisenteropathynon-ige-mediated |
| spellingShingle | S. G. Makarova T. E. Lavrova G. A. Novik Non-IgE-mediated gastrointestinal food allergy in children. Diagnostics, differential diagnostics, tactics of diet therapy Лечащий Врач food allergy cow's milk proteins diagnosis diet therapy enterocolitis proctocolitis enteropathy non-ige-mediated |
| title | Non-IgE-mediated gastrointestinal food allergy in children. Diagnostics, differential diagnostics, tactics of diet therapy |
| title_full | Non-IgE-mediated gastrointestinal food allergy in children. Diagnostics, differential diagnostics, tactics of diet therapy |
| title_fullStr | Non-IgE-mediated gastrointestinal food allergy in children. Diagnostics, differential diagnostics, tactics of diet therapy |
| title_full_unstemmed | Non-IgE-mediated gastrointestinal food allergy in children. Diagnostics, differential diagnostics, tactics of diet therapy |
| title_short | Non-IgE-mediated gastrointestinal food allergy in children. Diagnostics, differential diagnostics, tactics of diet therapy |
| title_sort | non ige mediated gastrointestinal food allergy in children diagnostics differential diagnostics tactics of diet therapy |
| topic | food allergy cow's milk proteins diagnosis diet therapy enterocolitis proctocolitis enteropathy non-ige-mediated |
| url | https://journal.lvrach.ru/jour/article/view/1081 |
| work_keys_str_mv | AT sgmakarova nonigemediatedgastrointestinalfoodallergyinchildrendiagnosticsdifferentialdiagnosticstacticsofdiettherapy AT telavrova nonigemediatedgastrointestinalfoodallergyinchildrendiagnosticsdifferentialdiagnosticstacticsofdiettherapy AT ganovik nonigemediatedgastrointestinalfoodallergyinchildrendiagnosticsdifferentialdiagnosticstacticsofdiettherapy |