Dual bombard by Cytomegalovirus and Mycobacterium tuberculosis in a renal transplantee
In the first year following an organ transplant, more than 80% of patients encounter a minimum of one occurrence of infection. Here, we report a case of coinfection of the Cytomegalovirus (CMV) and Mycobacterium tuberculosis (MTB) in a kidney transplantee. Computed tomography chest (CT chest) showed...
Saved in:
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2024-01-01
|
Series: | Journal of Current Research in Scientific Medicine |
Subjects: | |
Online Access: | https://journals.lww.com/10.4103/jcrsm.jcrsm_142_23 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832590888747925504 |
---|---|
author | Cinthujah Balachander Indira Ananthapadmanabasamy Ramasubramanian Viswanathan Poongodi Santhanakumarasamy |
author_facet | Cinthujah Balachander Indira Ananthapadmanabasamy Ramasubramanian Viswanathan Poongodi Santhanakumarasamy |
author_sort | Cinthujah Balachander |
collection | DOAJ |
description | In the first year following an organ transplant, more than 80% of patients encounter a minimum of one occurrence of infection. Here, we report a case of coinfection of the Cytomegalovirus (CMV) and Mycobacterium tuberculosis (MTB) in a kidney transplantee. Computed tomography chest (CT chest) showed bilateral ground-glass opacities. By Cytomegalovirus DNA polymerase chain reaction, 9360 copies were detected in plasma. Cartridge-based nucleic acid amplification test from bronchial washings tested positive for MTB with very low-level resistance to rifampicin. He was started on category-I antitubercular therapy without rifampicin and intravenous valganciclovir. The clinical status of the patient improved after 1 month of treatment. |
format | Article |
id | doaj-art-7283e2ae2de045f9b11ac6ef1c1367b7 |
institution | Kabale University |
issn | 2542-6273 2455-3069 |
language | English |
publishDate | 2024-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Current Research in Scientific Medicine |
spelling | doaj-art-7283e2ae2de045f9b11ac6ef1c1367b72025-01-23T05:27:27ZengWolters Kluwer Medknow PublicationsJournal of Current Research in Scientific Medicine2542-62732455-30692024-01-0110113013310.4103/jcrsm.jcrsm_142_23Dual bombard by Cytomegalovirus and Mycobacterium tuberculosis in a renal transplanteeCinthujah BalachanderIndira AnanthapadmanabasamyRamasubramanian ViswanathanPoongodi SanthanakumarasamyIn the first year following an organ transplant, more than 80% of patients encounter a minimum of one occurrence of infection. Here, we report a case of coinfection of the Cytomegalovirus (CMV) and Mycobacterium tuberculosis (MTB) in a kidney transplantee. Computed tomography chest (CT chest) showed bilateral ground-glass opacities. By Cytomegalovirus DNA polymerase chain reaction, 9360 copies were detected in plasma. Cartridge-based nucleic acid amplification test from bronchial washings tested positive for MTB with very low-level resistance to rifampicin. He was started on category-I antitubercular therapy without rifampicin and intravenous valganciclovir. The clinical status of the patient improved after 1 month of treatment.https://journals.lww.com/10.4103/jcrsm.jcrsm_142_23coinfectioncytomegalovirusrenal transplanttuberculosis |
spellingShingle | Cinthujah Balachander Indira Ananthapadmanabasamy Ramasubramanian Viswanathan Poongodi Santhanakumarasamy Dual bombard by Cytomegalovirus and Mycobacterium tuberculosis in a renal transplantee Journal of Current Research in Scientific Medicine coinfection cytomegalovirus renal transplant tuberculosis |
title | Dual bombard by Cytomegalovirus and Mycobacterium tuberculosis in a renal transplantee |
title_full | Dual bombard by Cytomegalovirus and Mycobacterium tuberculosis in a renal transplantee |
title_fullStr | Dual bombard by Cytomegalovirus and Mycobacterium tuberculosis in a renal transplantee |
title_full_unstemmed | Dual bombard by Cytomegalovirus and Mycobacterium tuberculosis in a renal transplantee |
title_short | Dual bombard by Cytomegalovirus and Mycobacterium tuberculosis in a renal transplantee |
title_sort | dual bombard by cytomegalovirus and mycobacterium tuberculosis in a renal transplantee |
topic | coinfection cytomegalovirus renal transplant tuberculosis |
url | https://journals.lww.com/10.4103/jcrsm.jcrsm_142_23 |
work_keys_str_mv | AT cinthujahbalachander dualbombardbycytomegalovirusandmycobacteriumtuberculosisinarenaltransplantee AT indiraananthapadmanabasamy dualbombardbycytomegalovirusandmycobacteriumtuberculosisinarenaltransplantee AT ramasubramanianviswanathan dualbombardbycytomegalovirusandmycobacteriumtuberculosisinarenaltransplantee AT poongodisanthanakumarasamy dualbombardbycytomegalovirusandmycobacteriumtuberculosisinarenaltransplantee |