RGD peptide-conjugated polydopamine nanoparticles loaded with doxorubicin for combined chemotherapy and photothermal therapy in thyroid cancer

RGD peptide-conjugated polydopamine nanoparticles loaded with doxorubicin for combined chemotherapy and photothermal therapy in thyroid cancer

Abstract Objective To construct polydopamine (PDA)-based nanoparticles (NPs) for combined chemotherapy (CT) and photothermal therapy (PTT) of thyroid tumors by conjugating doxorubicin (DOX) via Schiff base reaction and decorating with RGD peptide. Methods PDA NPs were synthesized using dopamine hydr...

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Bibliographic Details
Main Authors: Donglan Yuan, Zhiqiang Lu, Xindan Xu, Wei Liu
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Discover Oncology
Subjects:
Thyroid Cancer
RGD@PDA-DOX
Drug delivery
Photothermal therapy
Clinical transformation
Online Access:https://doi.org/10.1007/s12672-024-01682-x
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