Echocardiographic evidence for valvular toxicity of benfluorex: a double-blind randomised trial in patients with type 2 diabetes mellitus.

Echocardiographic evidence for valvular toxicity of benfluorex: a double-blind randomised trial in patients with type 2 diabetes mellitus.

<h4>Objectives</h4>REGULATE trial was designed to compare the efficacy and safety of benfluorex versus pioglitazone in type 2 diabetes mellitus (DM) patients.<h4>Methods</h4>Double-blind, parallel-group, international, randomised, non-inferiority trial. More than half of the...

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Main Authors: Geneviève Derumeaux, Laura Ernande, André Serusclat, Evelyne Servan, Eric Bruckert, Hugues Rousset, Stephen Senn, Luc Van Gaal, Brigitte Picandet, François Gavini, Philippe Moulin, REGULATE trial investigators
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0038273&type=printable
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