Experimental Models of Cryptococcosis
Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2012/626745 |
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| _version_ | 1849414666374086656 |
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| author | Wilber Sabiiti Robin C. May E. Rhiannon Pursall |
| author_facet | Wilber Sabiiti Robin C. May E. Rhiannon Pursall |
| author_sort | Wilber Sabiiti |
| collection | DOAJ |
| description | Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction. Here we review the range of experimental models that are available for cryptococcosis research and compare the relative advantages and limitations of the different systems. |
| format | Article |
| id | doaj-art-7270fe702e0e4700a39bd026fe527770 |
| institution | Kabale University |
| issn | 1687-918X 1687-9198 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Microbiology |
| spelling | doaj-art-7270fe702e0e4700a39bd026fe5277702025-08-20T03:33:45ZengWileyInternational Journal of Microbiology1687-918X1687-91982012-01-01201210.1155/2012/626745626745Experimental Models of CryptococcosisWilber Sabiiti0Robin C. May1E. Rhiannon Pursall2School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UKSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UKSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UKCryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction. Here we review the range of experimental models that are available for cryptococcosis research and compare the relative advantages and limitations of the different systems.http://dx.doi.org/10.1155/2012/626745 |
| spellingShingle | Wilber Sabiiti Robin C. May E. Rhiannon Pursall Experimental Models of Cryptococcosis International Journal of Microbiology |
| title | Experimental Models of Cryptococcosis |
| title_full | Experimental Models of Cryptococcosis |
| title_fullStr | Experimental Models of Cryptococcosis |
| title_full_unstemmed | Experimental Models of Cryptococcosis |
| title_short | Experimental Models of Cryptococcosis |
| title_sort | experimental models of cryptococcosis |
| url | http://dx.doi.org/10.1155/2012/626745 |
| work_keys_str_mv | AT wilbersabiiti experimentalmodelsofcryptococcosis AT robincmay experimentalmodelsofcryptococcosis AT erhiannonpursall experimentalmodelsofcryptococcosis |