Pediatric Bone Tumors: Location and Age Distribution of 420 Cases
Background/Objectives: One of the most important diagnostic tools in bone tumors is X-rays. Preliminary and, in the case of some benign lesions, definitive diagnoses are formed using this basic tool. Part of the decision making in this stage is based on statistical probability using the patient’s ag...
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MDPI AG
2024-11-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/14/22/2513 |
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| author | Sebastian Breden Maximilian Stephan Florian Hinterwimmer Sarah Consalvo Ulrich Lenze Rüdiger von Eisenhart-Rothe Carolin Mogler Alexandra S. Gersing Carolin Knebel |
| author_facet | Sebastian Breden Maximilian Stephan Florian Hinterwimmer Sarah Consalvo Ulrich Lenze Rüdiger von Eisenhart-Rothe Carolin Mogler Alexandra S. Gersing Carolin Knebel |
| author_sort | Sebastian Breden |
| collection | DOAJ |
| description | Background/Objectives: One of the most important diagnostic tools in bone tumors is X-rays. Preliminary and, in the case of some benign lesions, definitive diagnoses are formed using this basic tool. Part of the decision making in this stage is based on statistical probability using the patient’s age, as well as the incidence and predilection sites of different entities. The information used today is based on older and fragmented data. To verify the underlying principles, we retrospectively evaluated all bone tumors in children and adolescents treated by our tertiary center in the last 20 years. Methods: For this retrospective study, patients under the age of 18 years suffering from histopathologically verified bone tumors were evaluated. Data were retrieved from our local musculoskeletal tumor database. Results: We were able to include 420 children treated for bone tumors in our tertiary center. The cohort consisted of 335 benign and 85 malignant lesions. The most common lesions were 137 osteochondromas; the malignant tumors consisted mainly of osteosarcomas (53) and Ewing’s sarcomas (28). The primary predilection sites were the metaphyses of long bones. Conclusions: We were able to confirm and supplement the fragmentary data of these rare diseases using our own cohort. |
| format | Article |
| id | doaj-art-726b5d9c5f49426eb3ea820d17aeedb7 |
| institution | OA Journals |
| issn | 2075-4418 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj-art-726b5d9c5f49426eb3ea820d17aeedb72025-08-20T02:28:12ZengMDPI AGDiagnostics2075-44182024-11-011422251310.3390/diagnostics14222513Pediatric Bone Tumors: Location and Age Distribution of 420 CasesSebastian Breden0Maximilian Stephan1Florian Hinterwimmer2Sarah Consalvo3Ulrich Lenze4Rüdiger von Eisenhart-Rothe5Carolin Mogler6Alexandra S. Gersing7Carolin Knebel8Department of Orthopedics and Sports Orthopedics, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, GermanyDepartment of Orthopedics and Sports Orthopedics, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, GermanyDepartment of Orthopedics and Sports Orthopedics, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, GermanyDepartment of Orthopedics and Sports Orthopedics, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, GermanyDepartment of Orthopedics and Sports Orthopedics, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, GermanyDepartment of Orthopedics and Sports Orthopedics, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, GermanyGerman Working Group of Bone Tumors, 4031 Basel, SwitzerlandGerman Working Group of Bone Tumors, 4031 Basel, SwitzerlandDepartment of Orthopedics and Sports Orthopedics, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, GermanyBackground/Objectives: One of the most important diagnostic tools in bone tumors is X-rays. Preliminary and, in the case of some benign lesions, definitive diagnoses are formed using this basic tool. Part of the decision making in this stage is based on statistical probability using the patient’s age, as well as the incidence and predilection sites of different entities. The information used today is based on older and fragmented data. To verify the underlying principles, we retrospectively evaluated all bone tumors in children and adolescents treated by our tertiary center in the last 20 years. Methods: For this retrospective study, patients under the age of 18 years suffering from histopathologically verified bone tumors were evaluated. Data were retrieved from our local musculoskeletal tumor database. Results: We were able to include 420 children treated for bone tumors in our tertiary center. The cohort consisted of 335 benign and 85 malignant lesions. The most common lesions were 137 osteochondromas; the malignant tumors consisted mainly of osteosarcomas (53) and Ewing’s sarcomas (28). The primary predilection sites were the metaphyses of long bones. Conclusions: We were able to confirm and supplement the fragmentary data of these rare diseases using our own cohort.https://www.mdpi.com/2075-4418/14/22/2513pediatric cancersarcomamusculoskeletal tumordistribution patternlocalizationbone tumor |
| spellingShingle | Sebastian Breden Maximilian Stephan Florian Hinterwimmer Sarah Consalvo Ulrich Lenze Rüdiger von Eisenhart-Rothe Carolin Mogler Alexandra S. Gersing Carolin Knebel Pediatric Bone Tumors: Location and Age Distribution of 420 Cases Diagnostics pediatric cancer sarcoma musculoskeletal tumor distribution pattern localization bone tumor |
| title | Pediatric Bone Tumors: Location and Age Distribution of 420 Cases |
| title_full | Pediatric Bone Tumors: Location and Age Distribution of 420 Cases |
| title_fullStr | Pediatric Bone Tumors: Location and Age Distribution of 420 Cases |
| title_full_unstemmed | Pediatric Bone Tumors: Location and Age Distribution of 420 Cases |
| title_short | Pediatric Bone Tumors: Location and Age Distribution of 420 Cases |
| title_sort | pediatric bone tumors location and age distribution of 420 cases |
| topic | pediatric cancer sarcoma musculoskeletal tumor distribution pattern localization bone tumor |
| url | https://www.mdpi.com/2075-4418/14/22/2513 |
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