Pneumomediastinum following immunization of BioNTech COVID-19 vaccine: A coincidence?
Background: To build immunity against the pandemic severe acute respiratory syndrome coronavirus-2 infection in adolescents, wide-ranging immunization with BioNTech (BNT) vaccine was initiated in September 2021 in Taiwan. Some adverse events are, therefore, reported after vaccination. Herein, we sta...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-04-01
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| Series: | Pediatric Respirology and Critical Care Medicine |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/prcm.prcm_6_23 |
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| _version_ | 1850182863528394752 |
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| author | Shen-Hao Lai Sui-Ling Liao |
| author_facet | Shen-Hao Lai Sui-Ling Liao |
| author_sort | Shen-Hao Lai |
| collection | DOAJ |
| description | Background:
To build immunity against the pandemic severe acute respiratory syndrome coronavirus-2 infection in adolescents, wide-ranging immunization with BioNTech (BNT) vaccine was initiated in September 2021 in Taiwan. Some adverse events are, therefore, reported after vaccination. Herein, we stated a case series with uncommon pneumomediastinum after BNT vaccination.Materials and Methods:
This study retrospectively enrolled adolescents, who being diagnosed to have pneumomediastinum, during the 3-month period (between September 22, 2021, and December 22, 2021). Clinical information, such as clinical symptoms, radiographic characteristics, and clinical outcomes, were further analyzed.Results:
A total of eight adolescents developed pneumomediastinum during the 3-month period after BNT vaccination. The time interval between pneumomediastinum and vaccination showed bimodal peak (around 10 and 60 days after BNT vaccination). Significant Macklin effect can be sketched in radiographic images of six patients.Conclusion:
Several cases of pneumomediastinum were found in adolescents after BNT vaccination. The precise association is needed for further investigation. |
| format | Article |
| id | doaj-art-72680e8deef84ba2b553cf757dd8a19c |
| institution | OA Journals |
| issn | 2543-0343 2543-0351 |
| language | English |
| publishDate | 2023-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Pediatric Respirology and Critical Care Medicine |
| spelling | doaj-art-72680e8deef84ba2b553cf757dd8a19c2025-08-20T02:17:32ZengWolters Kluwer Medknow PublicationsPediatric Respirology and Critical Care Medicine2543-03432543-03512023-04-0172333610.4103/prcm.prcm_6_23Pneumomediastinum following immunization of BioNTech COVID-19 vaccine: A coincidence?Shen-Hao LaiSui-Ling LiaoBackground: To build immunity against the pandemic severe acute respiratory syndrome coronavirus-2 infection in adolescents, wide-ranging immunization with BioNTech (BNT) vaccine was initiated in September 2021 in Taiwan. Some adverse events are, therefore, reported after vaccination. Herein, we stated a case series with uncommon pneumomediastinum after BNT vaccination.Materials and Methods: This study retrospectively enrolled adolescents, who being diagnosed to have pneumomediastinum, during the 3-month period (between September 22, 2021, and December 22, 2021). Clinical information, such as clinical symptoms, radiographic characteristics, and clinical outcomes, were further analyzed.Results: A total of eight adolescents developed pneumomediastinum during the 3-month period after BNT vaccination. The time interval between pneumomediastinum and vaccination showed bimodal peak (around 10 and 60 days after BNT vaccination). Significant Macklin effect can be sketched in radiographic images of six patients.Conclusion: Several cases of pneumomediastinum were found in adolescents after BNT vaccination. The precise association is needed for further investigation.https://journals.lww.com/10.4103/prcm.prcm_6_23bnt vaccinecovid-19pneumomediastinumsars-cov-2 |
| spellingShingle | Shen-Hao Lai Sui-Ling Liao Pneumomediastinum following immunization of BioNTech COVID-19 vaccine: A coincidence? Pediatric Respirology and Critical Care Medicine bnt vaccine covid-19 pneumomediastinum sars-cov-2 |
| title | Pneumomediastinum following immunization of BioNTech COVID-19 vaccine: A coincidence? |
| title_full | Pneumomediastinum following immunization of BioNTech COVID-19 vaccine: A coincidence? |
| title_fullStr | Pneumomediastinum following immunization of BioNTech COVID-19 vaccine: A coincidence? |
| title_full_unstemmed | Pneumomediastinum following immunization of BioNTech COVID-19 vaccine: A coincidence? |
| title_short | Pneumomediastinum following immunization of BioNTech COVID-19 vaccine: A coincidence? |
| title_sort | pneumomediastinum following immunization of biontech covid 19 vaccine a coincidence |
| topic | bnt vaccine covid-19 pneumomediastinum sars-cov-2 |
| url | https://journals.lww.com/10.4103/prcm.prcm_6_23 |
| work_keys_str_mv | AT shenhaolai pneumomediastinumfollowingimmunizationofbiontechcovid19vaccineacoincidence AT suilingliao pneumomediastinumfollowingimmunizationofbiontechcovid19vaccineacoincidence |