Ureteropelvic Junction Obstruction and Parathyroid Adenoma: Coincidence or Link?
Congenital ureteropelvic junction obstruction (UPJO) is the most common cause of upper urinary tract obstruction in children. It is generally diagnosed in the routine work-up during antenatal period and is characterized by spontaneous recovery. It can be associated with urolithiasis; hence further i...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2017/9852912 |
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| author | Salah Termos Majd AlKabbani Tim Ulinski Sami Sanjad Henri Kotobi Francois Chalard Bilal Aoun |
| author_facet | Salah Termos Majd AlKabbani Tim Ulinski Sami Sanjad Henri Kotobi Francois Chalard Bilal Aoun |
| author_sort | Salah Termos |
| collection | DOAJ |
| description | Congenital ureteropelvic junction obstruction (UPJO) is the most common cause of upper urinary tract obstruction in children. It is generally diagnosed in the routine work-up during antenatal period and is characterized by spontaneous recovery. It can be associated with urolithiasis; hence further investigation should be carried out. We report the case of a 15-year-old boy, who is known to have right UPJO, presented with right renal colic and discovered to have bilateral kidney stones. Further studies showed primary hyperparathyroidism and genetic analysis revealed a CDC73 mutation (initially HRPT2). We believe that association of UPJO and PHPT is a rare coincidence that can be linked. Careful work-up of children with UPJO and urolithiasis is recommended to exclude an underlying metabolic disease. Surgical correction can be evitable as treatment of the primary cause can lead to complete dissolution of kidney stones and improvement of the medical condition. |
| format | Article |
| id | doaj-art-72663429483147b784248f001f08eaa6 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-72663429483147b784248f001f08eaa62025-02-03T05:47:41ZengWileyCase Reports in Nephrology2090-66412090-665X2017-01-01201710.1155/2017/98529129852912Ureteropelvic Junction Obstruction and Parathyroid Adenoma: Coincidence or Link?Salah Termos0Majd AlKabbani1Tim Ulinski2Sami Sanjad3Henri Kotobi4Francois Chalard5Bilal Aoun6Hepatobiliary and Transplant Unit, Department of Surgery, Al-Amiri Hospital, Kuwait City, KuwaitHepatobiliary and Transplant Unit, Department of Surgery, Al-Amiri Hospital, Kuwait City, KuwaitPediatric Nephrology, Armand Trousseau Hospital, APHP, Paris, FranceDivision of Pediatric Nephrology, Department of Pediatrics, American University of Beirut, Beirut, LebanonPediatric Nephrology, Armand Trousseau Hospital, APHP, Paris, FrancePediatric Nephrology, Armand Trousseau Hospital, APHP, Paris, FrancePediatric Nephrology, Armand Trousseau Hospital, APHP, Paris, FranceCongenital ureteropelvic junction obstruction (UPJO) is the most common cause of upper urinary tract obstruction in children. It is generally diagnosed in the routine work-up during antenatal period and is characterized by spontaneous recovery. It can be associated with urolithiasis; hence further investigation should be carried out. We report the case of a 15-year-old boy, who is known to have right UPJO, presented with right renal colic and discovered to have bilateral kidney stones. Further studies showed primary hyperparathyroidism and genetic analysis revealed a CDC73 mutation (initially HRPT2). We believe that association of UPJO and PHPT is a rare coincidence that can be linked. Careful work-up of children with UPJO and urolithiasis is recommended to exclude an underlying metabolic disease. Surgical correction can be evitable as treatment of the primary cause can lead to complete dissolution of kidney stones and improvement of the medical condition.http://dx.doi.org/10.1155/2017/9852912 |
| spellingShingle | Salah Termos Majd AlKabbani Tim Ulinski Sami Sanjad Henri Kotobi Francois Chalard Bilal Aoun Ureteropelvic Junction Obstruction and Parathyroid Adenoma: Coincidence or Link? Case Reports in Nephrology |
| title | Ureteropelvic Junction Obstruction and Parathyroid Adenoma: Coincidence or Link? |
| title_full | Ureteropelvic Junction Obstruction and Parathyroid Adenoma: Coincidence or Link? |
| title_fullStr | Ureteropelvic Junction Obstruction and Parathyroid Adenoma: Coincidence or Link? |
| title_full_unstemmed | Ureteropelvic Junction Obstruction and Parathyroid Adenoma: Coincidence or Link? |
| title_short | Ureteropelvic Junction Obstruction and Parathyroid Adenoma: Coincidence or Link? |
| title_sort | ureteropelvic junction obstruction and parathyroid adenoma coincidence or link |
| url | http://dx.doi.org/10.1155/2017/9852912 |
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