Neutralizing and enhancing monoclonal antibodies in SARS-CoV-2 convalescent patients: lessons from early variant infection and impact on shaping emerging variants

Neutralizing and enhancing monoclonal antibodies in SARS-CoV-2 convalescent patients: lessons from early variant infection and impact on shaping emerging variants

Serological studies of COVID-19 convalescent patients have identified polyclonal lineage-specific and cross-reactive antibodies (Abs), with varying effector functions against virus variants. Individual specificities of anti-SARS-CoV-2 Abs and their impact on infectivity by other variants have been l...

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Bibliographic Details
Main Authors: Frédéric Coutant, Franck Touret, Jean-Jacques Pin, Marina Alonzo, Cécile Baronti, Sandie Munier, Mikaël Attia, Xavier de Lamballerie, Tristan Ferry, Pierre Miossec
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
COVID-19
B cell repertoire
antibody-dependent enhancement
human monoclonal antibody
emerging variants
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2307510
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