Fibrous scaffolds loaded with BMSC-derived apoptotic vesicles promote wound healing by inducing macrophage polarization

Fibrous scaffolds loaded with BMSC-derived apoptotic vesicles promote wound healing by inducing macrophage polarization

Macrophages play a key role in wound healing. Dysfunction of their M0 polarization to M2 leads to disorders of the wound immune microenvironment and chronic inflammation, which affects wound healing. Regulating the polarization of M0 macrophages to M2 macrophages is an effective strategy for treatin...

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Bibliographic Details
Main Authors: Xudong Su, Jianye Yang, Zhenghao Xu, Li Wei, Shuhao Yang, Feilong Li, Min Sun, Yingkun Hu, Wenge He, Chen Zhao, Li Chen, Yonghua Yuan, Leilei Qin, Ning Hu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Genes and Diseases
Subjects:
Apoptotic body
Extracellular vesicles
Macrophage polarization
Mesenchymal stem cells
miR-21a-5p
Polycaprolactone
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304224001855
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