Sarcomatoid Carcinoma of the Oral Cavity: A Diagnostic Dilemma
Sarcomatoid carcinoma (SC) is a rare variant of squamous cell carcinoma which is characterized by a dysplastic epithelial component and a stromal element with invasive fusiform or spindle-shaped cells. The clinical and histopathologic characteristics make it very difficult to distinguish SC from epi...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2017/7495695 |
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| author | Anshul Mahajan Sujata Mohanty Sujoy Ghosh Aadithya B. Urs Nita Khurana Sunita Gupta |
| author_facet | Anshul Mahajan Sujata Mohanty Sujoy Ghosh Aadithya B. Urs Nita Khurana Sunita Gupta |
| author_sort | Anshul Mahajan |
| collection | DOAJ |
| description | Sarcomatoid carcinoma (SC) is a rare variant of squamous cell carcinoma which is characterized by a dysplastic epithelial component and a stromal element with invasive fusiform or spindle-shaped cells. The clinical and histopathologic characteristics make it very difficult to distinguish SC from epithelioid sarcoma (ES). We present a case of a 51-year-old man with a soft tissue mass in the oral cavity diagnosed as proximal variant of epithelioid sarcoma on incisional biopsy. A thorough radiologic examination was conducted to rule out the possibility of a primary elsewhere in the body. Supraomohyoid neck dissection, mandibular resection, and reconstruction with recon plates were carried out. Histopathologic examination was suggestive of epithelioid variant of SC which was contrary to the incisional biopsy report. The dilemma in diagnosis was resolved by observing the presence of invading atypical epithelial cells into the stroma confirming the epithelial origin of the tumor. |
| format | Article |
| id | doaj-art-7250b346808e4f13a7925139d4adfd40 |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-7250b346808e4f13a7925139d4adfd402025-02-03T06:46:05ZengWileyCase Reports in Dentistry2090-64472090-64552017-01-01201710.1155/2017/74956957495695Sarcomatoid Carcinoma of the Oral Cavity: A Diagnostic DilemmaAnshul Mahajan0Sujata Mohanty1Sujoy Ghosh2Aadithya B. Urs3Nita Khurana4Sunita Gupta5Department of Oral Medicine & Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, IndiaDepartment of Oral & Maxillofacial Surgery, Maulana Azad Institute of Dental Sciences, New Delhi, IndiaDepartment of Oral Medicine & Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, IndiaDepartment of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi, IndiaDepartment of Pathology, Maulana Azad Medical College, New Delhi, IndiaDepartment of Oral Medicine & Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, IndiaSarcomatoid carcinoma (SC) is a rare variant of squamous cell carcinoma which is characterized by a dysplastic epithelial component and a stromal element with invasive fusiform or spindle-shaped cells. The clinical and histopathologic characteristics make it very difficult to distinguish SC from epithelioid sarcoma (ES). We present a case of a 51-year-old man with a soft tissue mass in the oral cavity diagnosed as proximal variant of epithelioid sarcoma on incisional biopsy. A thorough radiologic examination was conducted to rule out the possibility of a primary elsewhere in the body. Supraomohyoid neck dissection, mandibular resection, and reconstruction with recon plates were carried out. Histopathologic examination was suggestive of epithelioid variant of SC which was contrary to the incisional biopsy report. The dilemma in diagnosis was resolved by observing the presence of invading atypical epithelial cells into the stroma confirming the epithelial origin of the tumor.http://dx.doi.org/10.1155/2017/7495695 |
| spellingShingle | Anshul Mahajan Sujata Mohanty Sujoy Ghosh Aadithya B. Urs Nita Khurana Sunita Gupta Sarcomatoid Carcinoma of the Oral Cavity: A Diagnostic Dilemma Case Reports in Dentistry |
| title | Sarcomatoid Carcinoma of the Oral Cavity: A Diagnostic Dilemma |
| title_full | Sarcomatoid Carcinoma of the Oral Cavity: A Diagnostic Dilemma |
| title_fullStr | Sarcomatoid Carcinoma of the Oral Cavity: A Diagnostic Dilemma |
| title_full_unstemmed | Sarcomatoid Carcinoma of the Oral Cavity: A Diagnostic Dilemma |
| title_short | Sarcomatoid Carcinoma of the Oral Cavity: A Diagnostic Dilemma |
| title_sort | sarcomatoid carcinoma of the oral cavity a diagnostic dilemma |
| url | http://dx.doi.org/10.1155/2017/7495695 |
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