A Case Report of X-Linked Hyperimmunoglobulin M Syndrome with Lipoma Arborescens of Knees
The X-linked hyperimmunoglobulin M syndrome (HIGM), caused by mutations in the CD40LG gene, is a kind of primary immunodeficiency disease (PID). Patients with X-linked HIGM are susceptible to infection as well as autoimmune diseases. Lipoma arborescens (LA) is a rare benign tumor, of which the patho...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/5797232 |
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| author | Qiuting Dong Jinxia Zhao Zhongqiang Yao Xiangyuan Liu Huiying He |
| author_facet | Qiuting Dong Jinxia Zhao Zhongqiang Yao Xiangyuan Liu Huiying He |
| author_sort | Qiuting Dong |
| collection | DOAJ |
| description | The X-linked hyperimmunoglobulin M syndrome (HIGM), caused by mutations in the CD40LG gene, is a kind of primary immunodeficiency disease (PID). Patients with X-linked HIGM are susceptible to infection as well as autoimmune diseases. Lipoma arborescens (LA) is a rare benign tumor, of which the pathogenesis mechanism has not been clearly understood. We report a case of HIGM combined with LA in a 22-year-old male patient. A new deletion mutation of CD40LG gene was detected in this case. The possible relationship between HIGM and LA was also discussed. |
| format | Article |
| id | doaj-art-7249d425e0574fbea109bc4fd1f7191e |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-7249d425e0574fbea109bc4fd1f7191e2025-02-03T06:00:51ZengWileyCase Reports in Medicine1687-96271687-96352016-01-01201610.1155/2016/57972325797232A Case Report of X-Linked Hyperimmunoglobulin M Syndrome with Lipoma Arborescens of KneesQiuting Dong0Jinxia Zhao1Zhongqiang Yao2Xiangyuan Liu3Huiying He4Department of Rheumatology & Immunology, Peking University Third Hospital, 49 North Garden Rd., Haidian District, Beijing 100191, ChinaDepartment of Rheumatology & Immunology, Peking University Third Hospital, 49 North Garden Rd., Haidian District, Beijing 100191, ChinaDepartment of Rheumatology & Immunology, Peking University Third Hospital, 49 North Garden Rd., Haidian District, Beijing 100191, ChinaDepartment of Rheumatology & Immunology, Peking University Third Hospital, 49 North Garden Rd., Haidian District, Beijing 100191, ChinaDepartment of Pathology, Peking University Third Hospital, 49 North Garden Rd., Haidian District, Beijing 100191, ChinaThe X-linked hyperimmunoglobulin M syndrome (HIGM), caused by mutations in the CD40LG gene, is a kind of primary immunodeficiency disease (PID). Patients with X-linked HIGM are susceptible to infection as well as autoimmune diseases. Lipoma arborescens (LA) is a rare benign tumor, of which the pathogenesis mechanism has not been clearly understood. We report a case of HIGM combined with LA in a 22-year-old male patient. A new deletion mutation of CD40LG gene was detected in this case. The possible relationship between HIGM and LA was also discussed.http://dx.doi.org/10.1155/2016/5797232 |
| spellingShingle | Qiuting Dong Jinxia Zhao Zhongqiang Yao Xiangyuan Liu Huiying He A Case Report of X-Linked Hyperimmunoglobulin M Syndrome with Lipoma Arborescens of Knees Case Reports in Medicine |
| title | A Case Report of X-Linked Hyperimmunoglobulin M Syndrome with Lipoma Arborescens of Knees |
| title_full | A Case Report of X-Linked Hyperimmunoglobulin M Syndrome with Lipoma Arborescens of Knees |
| title_fullStr | A Case Report of X-Linked Hyperimmunoglobulin M Syndrome with Lipoma Arborescens of Knees |
| title_full_unstemmed | A Case Report of X-Linked Hyperimmunoglobulin M Syndrome with Lipoma Arborescens of Knees |
| title_short | A Case Report of X-Linked Hyperimmunoglobulin M Syndrome with Lipoma Arborescens of Knees |
| title_sort | case report of x linked hyperimmunoglobulin m syndrome with lipoma arborescens of knees |
| url | http://dx.doi.org/10.1155/2016/5797232 |
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