Engineering Saccharomyces cerevisiae for the production of natural osmolyte glucosyl glycerol from sucrose and glycerol through Ccw12-based surface display of sucrose phosphorylase

Engineering Saccharomyces cerevisiae for the production of natural osmolyte glucosyl glycerol from sucrose and glycerol through Ccw12-based surface display of sucrose phosphorylase

Abstract Background Yeast Saccharomyces cerevisiae is widely recognised as a versatile chassis for constructing microbial cell factories. However, producing chemicals from toxic, highly concentrated, or cell-impermeable substrates, or chemicals dependent on enzymatic reactions incompatible with the...

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Bibliographic Details
Main Authors: Tea Martinić Cezar, Nenad Marđetko, Antonija Trontel, Antonia Paić, Anita Slavica, Renata Teparić, Bojan Žunar
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Biological Engineering
Subjects:
Glucosyl glycerol
Osmolyte
Sucrose phosphorylase
Saccharomyces cerevisiae
Surface display
Ccw12
Online Access:https://doi.org/10.1186/s13036-024-00468-7
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