The function of T cells in immune thrombocytopenia

The function of T cells in immune thrombocytopenia

Immune thrombocytopenia (ITP) is an autoimmune disease, characterized by increased bleeding due to a reduced platelet count. The pathogenesis of ITP is very complex and involves autoantibody production and T-cell-mediated immune abnormalities. An imbalance of effector and regulatory CD4+ T cells and...

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Bibliographic Details
Main Authors: Siyuan Bu, Min Liu, Lu Yang, Pamela Lee, Heather Miller, Chan-Sik Park, Maria Byazrova, Alexander Filatov, Kamel Benlagha, Timo Gaber, Frank Buttgereit, Quan Gong, Zhimin Zhai, Chaohong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
immune thrombocytopenia
CD4+T cell
CD8 + T cell
genetic factors
T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1499014/full
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