Comparative analysis of clinical features, methylation and immune microenvironment in pediatric and adult papillary craniopharyngiomas: results from a multicenter study

Comparative analysis of clinical features, methylation and immune microenvironment in pediatric and adult papillary craniopharyngiomas: results from a multicenter study

Abstract Papillary craniopharyngioma (PCP) was previously believed to occur only in adults. Sporadic pediatric PCP (PPCP), confirmed by detection of the BRAF V600E mutation, has been reported since 2018. The differences between PPCP and adult PCP (APCP) remain unclear. This comprehensive study aimed...

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Bibliographic Details
Main Authors: Ning Luo, Yi Lin, Jing Feng, Linbo Cai, Yongli Zhang, Xingfu Wang, Wenzhong Mei, Hao Li, Bei Liu, Xueling Qi, Zhixiong Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Papillary craniopharyngioma
Pediatric
Adult
Diagnosis
Pathophysiology
Online Access:https://doi.org/10.1038/s41598-025-12662-8
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