Vaccination status and clinical outcome of COVID-19 in hospitalized patients
Objective: to analyze the relationship between the vaccination status of patients hospitalized for COVID-19 and clinical outcomes. Methods: retrospective cohort study conducted at a referral hospital for COVID-19, including 305 patients ≥ 5 years of age admitted to wards and/or intensive care units...
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| Format: | Article |
| Language: | English |
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Universidade Federal do Ceará
2025-08-01
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| Series: | Rev Rene |
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| Online Access: | https://periodicos.ufc.br/rene/article/view/95529/252043 |
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| _version_ | 1849392645966659584 |
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| author | Priscila Poli Gustavo Diego Magno Silvia Carla da Silva André Uehara |
| author_facet | Priscila Poli Gustavo Diego Magno Silvia Carla da Silva André Uehara |
| author_sort | Priscila Poli |
| collection | DOAJ |
| description | Objective: to analyze the relationship between the vaccination status of patients hospitalized for COVID-19 and clinical outcomes. Methods: retrospective cohort study conducted at a referral hospital for COVID-19, including 305 patients ≥ 5 years of age admitted to wards and/or intensive care units with a diagnosis of COVID-19. Hospitalization data were collected from electronic medical records, and vaccination status data were obtained from the VaciVida system. The analysis was performed using Poisson regression models. Results: the comparison between patients who did not receive any vaccine doses and those who received a booster dose showed a relative risk of 1.46 (p = 0.160), suggesting an increased risk of death among the unvaccinated; however, this was not statistically significant. The comparison between unvaccinated individuals and those with an incomplete vaccination schedule revealed a relative risk of 2.42 (p = 0.350). Conclusion: it was observed that most patients who died or required intensive care did not have a complete vaccination schedule, which points to a possible trend toward worse outcomes among unvaccinated individuals. Contributions to practice: the findings underscore the importance of vaccination and active surveillance of clinical factors associated with severity to inform management in patients with COVID-19. |
| format | Article |
| id | doaj-art-720c533fb65347299caaf6566c6893e5 |
| institution | Kabale University |
| issn | 2175-6783 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Universidade Federal do Ceará |
| record_format | Article |
| series | Rev Rene |
| spelling | doaj-art-720c533fb65347299caaf6566c6893e52025-08-20T03:40:44ZengUniversidade Federal do CearáRev Rene2175-67832025-08-0126e9552910.36517/2175-6783.20252695529Vaccination status and clinical outcome of COVID-19 in hospitalized patientsPriscila Poli0https://orcid.org/0000-0002-8090-9403Gustavo Diego Magno1https://orcid.org/0000-0003-3656-9170Silvia Carla da Silva André Uehara2https://orcid.org/0000-0002-0236-5025Universidade Federal de São CarlosUniversidade Federal de São CarlosUniversidade Federal de São CarlosObjective: to analyze the relationship between the vaccination status of patients hospitalized for COVID-19 and clinical outcomes. Methods: retrospective cohort study conducted at a referral hospital for COVID-19, including 305 patients ≥ 5 years of age admitted to wards and/or intensive care units with a diagnosis of COVID-19. Hospitalization data were collected from electronic medical records, and vaccination status data were obtained from the VaciVida system. The analysis was performed using Poisson regression models. Results: the comparison between patients who did not receive any vaccine doses and those who received a booster dose showed a relative risk of 1.46 (p = 0.160), suggesting an increased risk of death among the unvaccinated; however, this was not statistically significant. The comparison between unvaccinated individuals and those with an incomplete vaccination schedule revealed a relative risk of 2.42 (p = 0.350). Conclusion: it was observed that most patients who died or required intensive care did not have a complete vaccination schedule, which points to a possible trend toward worse outcomes among unvaccinated individuals. Contributions to practice: the findings underscore the importance of vaccination and active surveillance of clinical factors associated with severity to inform management in patients with COVID-19.https://periodicos.ufc.br/rene/article/view/95529/252043covid-19hospitalizationoutcome expectationscovid-19 vaccines |
| spellingShingle | Priscila Poli Gustavo Diego Magno Silvia Carla da Silva André Uehara Vaccination status and clinical outcome of COVID-19 in hospitalized patients Rev Rene covid-19 hospitalization outcome expectations covid-19 vaccines |
| title | Vaccination status and clinical outcome of COVID-19 in hospitalized patients |
| title_full | Vaccination status and clinical outcome of COVID-19 in hospitalized patients |
| title_fullStr | Vaccination status and clinical outcome of COVID-19 in hospitalized patients |
| title_full_unstemmed | Vaccination status and clinical outcome of COVID-19 in hospitalized patients |
| title_short | Vaccination status and clinical outcome of COVID-19 in hospitalized patients |
| title_sort | vaccination status and clinical outcome of covid 19 in hospitalized patients |
| topic | covid-19 hospitalization outcome expectations covid-19 vaccines |
| url | https://periodicos.ufc.br/rene/article/view/95529/252043 |
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